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Pharmacokinetic, pharmacodynamic, and transcriptomic analysis of chronic levetiracetam treatment in 5XFAD mice: A MODEL-AD preclinical testing core study.
Onos KD, Quinney SK, Jones DR, Masters AR, Pandey R, Keezer KJ, Biesdorf C, Metzger IF, Meyers JA, Peters J, Persohn SC, McCarthy BP, Bedwell AA, Figueiredo LL, Cope ZA, Sasner M, Howell GR, Williams HM, Oblak AL, Lamb BT, Carter GW, Rizzo SJS, Territo PR. Onos KD, et al. Among authors: keezer kj. Alzheimers Dement (N Y). 2022 Aug 23;8(1):e12329. doi: 10.1002/trc2.12329. eCollection 2022. Alzheimers Dement (N Y). 2022. PMID: 36016830 Free PMC article.
Prophylactic evaluation of verubecestat on disease- and symptom-modifying effects in 5XFAD mice.
Oblak AL, Cope ZA, Quinney SK, Pandey RS, Biesdorf C, Masters AR, Onos KD, Haynes L, Keezer KJ, Meyer JA, Peters JS, Persohn SA, Bedwell AA, Eldridge K, Speedy R, Little G, Williams SP, Noarbe B, Obenaus A, Sasner M, Howell GR, Carter GW, Williams H, Lamb BT, Territo PR, Sukoff Rizzo SJ. Oblak AL, et al. Among authors: keezer kj. Alzheimers Dement (N Y). 2022 Jul 14;8(1):e12317. doi: 10.1002/trc2.12317. eCollection 2022. Alzheimers Dement (N Y). 2022. PMID: 35846156 Free PMC article.
Meox2 Haploinsufficiency Accelerates Axonal Degeneration in DBA/2J Glaucoma.
Buchanan RA, Foley KE, Pepper KW, Reagan AM, Keezer KJ, Hewes AA, Diemler CA, Preuss C, Soto I, John SWM, Howell GR. Buchanan RA, et al. Among authors: keezer kj. Invest Ophthalmol Vis Sci. 2019 Aug 1;60(10):3283-3296. doi: 10.1167/iovs.18-26126. Invest Ophthalmol Vis Sci. 2019. PMID: 31369031 Free PMC article.