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165 results

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Page 1
Microenvironmental stiffness induces metabolic reprogramming in glioblastoma.
Sohrabi A, Lefebvre AEYT, Harrison MJ, Condro MC, Sanazzaro TM, Safarians G, Solomon I, Bastola S, Kordbacheh S, Toh N, Kornblum HI, Digman MA, Seidlits SK. Sohrabi A, et al. Among authors: kornblum hi. Cell Rep. 2023 Oct 31;42(10):113175. doi: 10.1016/j.celrep.2023.113175. Epub 2023 Sep 26. Cell Rep. 2023. PMID: 37756163 Free PMC article.
Glioblastoma Spheroid Invasion through Soft, Brain-Like Matrices Depends on Hyaluronic Acid-CD44 Interactions.
Safarians G, Sohrabi A, Solomon I, Xiao W, Bastola S, Rajput BW, Epperson M, Rosenzweig I, Tamura K, Singer B, Huang J, Harrison MJ, Sanazzaro T, Condro MC, Kornblum HI, Seidlits SK. Safarians G, et al. Among authors: kornblum hi. Adv Healthc Mater. 2023 Jun;12(14):e2203143. doi: 10.1002/adhm.202203143. Epub 2023 Feb 8. Adv Healthc Mater. 2023. PMID: 36694362 Free PMC article.
Valproic acid targets IDH1 mutants through alteration of lipid metabolism.
Elahi LS, Condro MC, Kawaguchi R, Qin Y, Alvarado AG, Gruender B, Qi H, Li T, Lai A, Castro MG, Lowenstein PR, Garrett MC, Kornblum HI. Elahi LS, et al. Among authors: kornblum hi. NPJ Metab Health Dis. 2024;2(1):20. doi: 10.1038/s44324-024-00021-6. Epub 2024 Aug 13. NPJ Metab Health Dis. 2024. PMID: 39149696 Free PMC article.
M2 isoform of pyruvate kinase rewires glucose metabolism during radiation therapy to promote an antioxidant response and glioblastoma radioresistance.
Bailleul J, Ruan Y, Abdulrahman L, Scott AJ, Yazal T, Sung D, Park K, Hoang H, Nathaniel J, Chu FI, Palomera D, Sehgal A, Tsang JE, Nathanson DA, Xu S, Park JO, Ten Hoeve J, Bhat K, Qi N, Kornblum HI, Schaue D, McBride WH, Lyssiotis CA, Wahl DR, Vlashi E. Bailleul J, et al. Among authors: kornblum hi. Neuro Oncol. 2023 Nov 2;25(11):1989-2000. doi: 10.1093/neuonc/noad103. Neuro Oncol. 2023. PMID: 37279645 Free PMC article.
HDAC1 and HDAC6 are essential for driving growth in IDH1 mutant glioma.
Garrett MC, Albano R, Carnwath T, Elahi L, Behrmann CA, Pemberton M, Woo D, O'Brien E, VanCauwenbergh B, Perentesis J, Shah S, Hagan M, Kendler A, Zhao C, Paranjpe A, Roskin K, Kornblum H, Plas DR, Lu QR. Garrett MC, et al. Sci Rep. 2023 Aug 1;13(1):12433. doi: 10.1038/s41598-023-33889-3. Sci Rep. 2023. PMID: 37528157 Free PMC article.
Acute rapamycin treatment reveals novel mechanisms of behavioral, physiological, and functional dysfunction in a maternal inflammation mouse model of autism and sensory over-responsivity.
Le Belle JE, Condro M, Cepeda C, Oikonomou KD, Tessema K, Dudley L, Schoenfield J, Kawaguchi R, Geschwind D, Silva AJ, Zhang Z, Shokat K, Harris NG, Kornblum HI. Le Belle JE, et al. Among authors: kornblum hi. bioRxiv [Preprint]. 2024 Jul 11:2024.07.08.602602. doi: 10.1101/2024.07.08.602602. bioRxiv. 2024. PMID: 39026891 Free PMC article. Preprint.
Interfer(on)ing with Zika virus.
Alvarado AG, Kornblum HI. Alvarado AG, et al. Among authors: kornblum hi. Neuron. 2022 Dec 7;110(23):3853-3854. doi: 10.1016/j.neuron.2022.10.027. Neuron. 2022. PMID: 36480937 Free article.
Activation of the mevalonate pathway in response to anti-cancer treatments drives glioblastoma recurrences through activation of Rac-1.
He L, Ioannidis A, Arambula E, Hoffman CJ, Joshi P, Kathiravan A, Whitelegge J, Liau LM, Kornblum HI, Pajonk F. He L, et al. Among authors: kornblum hi. bioRxiv [Preprint]. 2023 Jul 25:2023.07.23.550205. doi: 10.1101/2023.07.23.550205. bioRxiv. 2023. Update in: Cancer Res Commun. 2024 Jun 25;4(6):1566-1580. doi: 10.1158/2767-9764.CRC-24-0049 PMID: 37546917 Free PMC article. Updated. Preprint.
165 results