Beadle JR - Search Results

1

Enhanced broad spectrum in vitro antiviral efficacy of 3-F-4-MeO-Bn, 3-CN, and 4-CN derivatives of lipid remdesivir nucleoside monophosphate prodrugs.

McMillan RE, Lo MK, Zhang XQ, Beadle JR, Valiaeva N, Garretson AF, Clark AE, Freshman JE, Murphy J, Montgomery JM, Spiropoulou CF, Schooley RT, Hostetler KY, Carlin AF. McMillan RE, et al. Among authors: beadle jr. Antiviral Res. 2023 Nov;219:105718. doi: 10.1016/j.antiviral.2023.105718. Epub 2023 Sep 25. Antiviral Res. 2023. PMID: 37758067 Free PMC article.

2

Sugar substitutes: their energy values, bulk characteristics, and potential health benefits.

Levin GV, Zehner LR, Saunders JP, Beadle JR. Levin GV, et al. Among authors: beadle jr. Am J Clin Nutr. 1995 Nov;62(5 Suppl):1161S-1168S. doi: 10.1093/ajcn/62.5.1161S. Am J Clin Nutr. 1995. PMID: 7484937 Review.

3

Lipid prodrugs of phosphonoacids: greatly enhanced antiviral activity of 1-O-octadecyl-sn-glycero-3-phosphonoformate in HIV-1, HSV-1 and HCMV-infected cells, in vitro.

Hostetler KY, Kini GD, Beadle JR, Aldern KA, Gardner MF, Border R, Kumar R, Barshak L, Sridhar CN, Wheeler CJ, Richman DD. Hostetler KY, et al. Among authors: beadle jr. Antiviral Res. 1996 Jun;31(1-2):59-67. doi: 10.1016/0166-3542(96)00947-3. Antiviral Res. 1996. PMID: 8793009

4

Enhanced oral absorption and antiviral activity of 1-O-octadecyl-sn-glycero-3-phospho-acyclovir and related compounds in hepatitis B virus infection, in vitro.

Hostetler KY, Beadle JR, Kini GD, Gardner MF, Wright KN, Wu TH, Korba BA. Hostetler KY, et al. Among authors: beadle jr. Biochem Pharmacol. 1997 Jun 15;53(12):1815-22. doi: 10.1016/s0006-2952(97)82446-x. Biochem Pharmacol. 1997. PMID: 9256156 Free article.

5

Alkoxy propane prodrugs of foscarnet: effect of alkyl chain length on in vitro antiviral activity in cells infected with HIV-1, HSV-1 and HCMV.

Kini GD, Beadle JR, Xie H, Aldern KA, Richman DD, Hostetler KY. Kini GD, et al. Among authors: beadle jr. Antiviral Res. 1997 Sep;36(1):43-53. doi: 10.1016/s0166-3542(97)00039-9. Antiviral Res. 1997. PMID: 9330760

6

Synthesis and antiviral activity of 1-O-octadecyl-2-O-alkyl-sn-glycero-3-foscarnet conjugates in human cytomegalovirus-infected cells.

Kini GD, Hostetler SE, Beadle JR, Aldern KA. Kini GD, et al. Among authors: beadle jr. Antiviral Res. 1997 Nov;36(2):115-24. doi: 10.1016/s0166-3542(97)00048-x. Antiviral Res. 1997. PMID: 9443668

7

Alkylthioglycerol prodrugs of foscarnet: synthesis, oral bioavailability and structure-activity studies in human cytomegalovirus-, herpes simplex virus type 1- and human immunodeficiency virus type 1-infected cells.

Beadle JR, Kini GD, Aldern KA, Gardner MF, Wright KN, Richman DD, Hostetler KY. Beadle JR, et al. Antivir Chem Chemother. 1998 Jan;9(1):33-40. doi: 10.1177/095632029800900104. Antivir Chem Chemother. 1998. PMID: 9875375

8

Intravitreal toxicology and therapeutic efficacy of the carboxymethyl ester of the 1-O-octadecyl-sn-glycerol-3-phosphonoformate (ODG-PFA-O-Me), a novel lipid antiviral prodrug for intraocular drug delivery.

Cheng L, Hostetler KY, Gardner MF, Avila CP Jr, Bergeron-Lynn G, Keefe KS, Beadle JR, Wiley CA, Freeman WR. Cheng L, et al. Among authors: beadle jr. J Ocul Pharmacol Ther. 1999 Aug;15(4):363-77. doi: 10.1089/jop.1999.15.363. J Ocul Pharmacol Ther. 1999. PMID: 10463875

9

Synthesis and antiviral evaluation of 1-O-hexadecylpropanediol-3-P-acyclovir: efficacy against HSV-1 infection in mice.

Beadle JR, Kini GD, Aldern KA, Gardner MF, Wright KN, Rybak RJ, Kern ER, Hostetler KY. Beadle JR, et al. Nucleosides Nucleotides Nucleic Acids. 2000 Jan-Feb;19(1-2):471-9. doi: 10.1080/15257770008033022. Nucleosides Nucleotides Nucleic Acids. 2000. PMID: 10772728

10

Intravitreal toxicology and duration of efficacy of a novel antiviral lipid prodrug of ganciclovir in liposome formulation.

Cheng L, Hostetler KY, Chaidhawangul S, Gardner MF, Beadle JR, Keefe KS, Bergeron-Lynn G, Severson GM, Soules KA, Mueller AJ, Freeman WR. Cheng L, et al. Among authors: beadle jr. Invest Ophthalmol Vis Sci. 2000 May;41(6):1523-32. Invest Ophthalmol Vis Sci. 2000. PMID: 10798672

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