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Investigation of the absolute bioavailability, mass balance, metabolism, and excretion of the cholesterol 24-hydroxylase inhibitor soticlestat in healthy volunteers.
Yin W, Ballard TE, Zhu SX, Hsiao S, Chen H, Li Y, Chowdhury SK, Stevenson A, Hui T, Hunt A, Asgharnejad M, Han S. Yin W, et al. Among authors: stevenson a. Br J Clin Pharmacol. 2024 Feb;90(2):516-527. doi: 10.1111/bcp.15917. Epub 2023 Nov 12. Br J Clin Pharmacol. 2024. PMID: 37771051 Clinical Trial.
Effects of Strong Inhibition of Cytochrome P450 3A and UDP glucuronosyltransferase 1A9 and Strong Induction of Cytochrome P450 3A on the Pharmacokinetics, Safety, and Tolerability of Soticlestat: Two Drug-Drug Interaction Studies in Healthy Volunteers.
Yin W, Dong C, Stevenson A, Lloyd V, Petrillo M, Baratta M, Hui T, Han S. Yin W, et al. Among authors: stevenson a. Drug Metab Dispos. 2024 Feb 14;52(3):180-187. doi: 10.1124/dmd.123.001444. Drug Metab Dispos. 2024. PMID: 38123352
A new class of penicillin-binding protein inhibitors to address drug-resistant Neisseria gonorrhoeae.
Uehara T, Zulli AL, Miller B, Avery LM, Boyd SA, Chatwin CL, Chu GH, Drager AS, Edwards M, Emeigh Hart SG, Myers CL, Rongala G, Stevenson A, Uehara K, Yi F, Wang B, Liu Z, Wang M, Zhao Z, Zhou X, Zhao H, Stratton CM, Bala S, Davies C, Tkavc R, Jerse AE, Pevear DC, Burns CJ, Daigle DM, Condon SM. Uehara T, et al. Among authors: stevenson a. bioRxiv [Preprint]. 2024 Dec 27:2024.12.27.630553. doi: 10.1101/2024.12.27.630553. bioRxiv. 2024. PMID: 39763734 Free PMC article. Preprint.
998 results