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Preliminary results from the EMoLung clinical study showing early lung cancer detection by the LC score.
Rubio K, Müller JM, Mehta A, Watermann I, Olchers T, Koch I, Wessels S, Schneider MA, Araujo-Ramos T, Singh I, Kugler C, Stoleriu MG, Kriegsmann M, Eichhorn M, Muley T, Merkel OM, Braun T, Ammerpohl O, Reck M, Tresch A, Barreto G. Rubio K, et al. Among authors: merkel om. Discov Oncol. 2023 Oct 3;14(1):181. doi: 10.1007/s12672-023-00799-9. Discov Oncol. 2023. PMID: 37787775 Free PMC article.
Immunogenicity of Cas9 Protein.
Mehta A, Merkel OM. Mehta A, et al. Among authors: merkel om. J Pharm Sci. 2020 Jan;109(1):62-67. doi: 10.1016/j.xphs.2019.10.003. Epub 2019 Oct 4. J Pharm Sci. 2020. PMID: 31589876 Free PMC article.
Targeting genomic SARS-CoV-2 RNA with siRNAs allows efficient inhibition of viral replication and spread.
Ambike S, Cheng CC, Feuerherd M, Velkov S, Baldassi D, Afridi SQ, Porras-Gonzalez D, Wei X, Hagen P, Kneidinger N, Stoleriu MG, Grass V, Burgstaller G, Pichlmair A, Merkel OM, Ko C, Michler T. Ambike S, et al. Among authors: merkel om. Nucleic Acids Res. 2022 Jan 11;50(1):333-349. doi: 10.1093/nar/gkab1248. Nucleic Acids Res. 2022. PMID: 34928377 Free PMC article.
Inhibition of SARS-CoV-2 replication in the lung with siRNA/VIPER polyplexes.
Baldassi D, Ambike S, Feuerherd M, Cheng CC, Peeler DJ, Feldmann DP, Porras-Gonzalez DL, Wei X, Keller LA, Kneidinger N, Stoleriu MG, Popp A, Burgstaller G, Pun SH, Michler T, Merkel OM. Baldassi D, et al. Among authors: merkel om. J Control Release. 2022 May;345:661-674. doi: 10.1016/j.jconrel.2022.03.051. Epub 2022 Mar 29. J Control Release. 2022. PMID: 35364120 Free PMC article.
Spray drying siRNA-lipid nanoparticles for dry powder pulmonary delivery.
Zimmermann CM, Baldassi D, Chan K, Adams NBP, Neumann A, Porras-Gonzalez DL, Wei X, Kneidinger N, Stoleriu MG, Burgstaller G, Witzigmann D, Luciani P, Merkel OM. Zimmermann CM, et al. Among authors: merkel om. J Control Release. 2022 Nov;351:137-150. doi: 10.1016/j.jconrel.2022.09.021. Epub 2022 Sep 22. J Control Release. 2022. PMID: 36126785 Free PMC article.
118 results