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Page 1
Negative feedback regulation of MAPK signaling is an important driver of chronic lymphocytic leukemia progression.
Ecker V, Brandmeier L, Stumpf M, Giansanti P, Moreira AV, Pfeuffer L, Fens MHAM, Lu J, Kuster B, Engleitner T, Heidegger S, Rad R, Ringshausen I, Zenz T, Wendtner CM, Müschen M, Jellusova J, Ruland J, Buchner M. Ecker V, et al. Cell Rep. 2023 Oct 31;42(10):113017. doi: 10.1016/j.celrep.2023.113017. Epub 2023 Oct 4. Cell Rep. 2023. PMID: 37792532 Free article.
Targeted PI3K/AKT-hyperactivation induces cell death in chronic lymphocytic leukemia.
Ecker V, Stumpf M, Brandmeier L, Neumayer T, Pfeuffer L, Engleitner T, Ringshausen I, Nelson N, Jücker M, Wanninger S, Zenz T, Wendtner C, Manske K, Steiger K, Rad R, Müschen M, Ruland J, Buchner M. Ecker V, et al. Nat Commun. 2021 Jun 10;12(1):3526. doi: 10.1038/s41467-021-23752-2. Nat Commun. 2021. PMID: 34112805 Free PMC article.
Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer.
Sadras T, Martin M, Kume K, Robinson ME, Saravanakumar S, Lenz G, Chen Z, Song JY, Siddiqi T, Oksa L, Knapp AM, Cutler J, Cosgun KN, Klemm L, Ecker V, Winchester J, Ghergus D, Soulas-Sprauel P, Kiefer F, Heisterkamp N, Pandey A, Ngo V, Wang L, Jumaa H, Buchner M, Ruland J, Chan WC, Meffre E, Martin T, Müschen M. Sadras T, et al. Among authors: ecker v. Mol Cell. 2021 May 20;81(10):2094-2111.e9. doi: 10.1016/j.molcel.2021.03.043. Epub 2021 Apr 19. Mol Cell. 2021. PMID: 33878293 Free PMC article.
Nanomedicines for the treatment of hematological malignancies.
Deshantri AK, Varela Moreira A, Ecker V, Mandhane SN, Schiffelers RM, Buchner M, Fens MHAM. Deshantri AK, et al. Among authors: ecker v. J Control Release. 2018 Oct 10;287:194-215. doi: 10.1016/j.jconrel.2018.08.034. Epub 2018 Aug 28. J Control Release. 2018. PMID: 30165140 Review.
Stromal cell protein kinase C-β inhibition enhances chemosensitivity in B cell malignancies and overcomes drug resistance.
Park E, Chen J, Moore A, Mangolini M, Santoro A, Boyd JR, Schjerven H, Ecker V, Buchner M, Williamson JC, Lehner PJ, Gasparoli L, Williams O, Bloehdorn J, Stilgenbauer S, Leitges M, Egle A, Schmidt-Supprian M, Frietze S, Ringshausen I. Park E, et al. Among authors: ecker v. Sci Transl Med. 2020 Jan 15;12(526):eaax9340. doi: 10.1126/scitranslmed.aax9340. Sci Transl Med. 2020. PMID: 31941829 Free PMC article.
A novel bispecific EGFR/Met antibody blocks tumor-promoting phenotypic effects induced by resistance to EGFR inhibition and has potent antitumor activity.
Castoldi R, Ecker V, Wiehle L, Majety M, Busl-Schuller R, Asmussen M, Nopora A, Jucknischke U, Osl F, Kobold S, Scheuer W, Venturi M, Klein C, Niederfellner G, Sustmann C. Castoldi R, et al. Among authors: ecker v. Oncogene. 2013 Dec 12;32(50):5593-601. doi: 10.1038/onc.2013.245. Epub 2013 Jul 1. Oncogene. 2013. PMID: 23812422 Free PMC article.
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