Caputo AT - Search Results

1

A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint.

Guay KP, Ibba R, Kiappes JL, Vasiljević S, Bonì F, De Benedictis M, Zeni I, Le Cornu JD, Hensen M, Chandran AV, Kantsadi AL, Caputo AT, Blanco Capurro JI, Bayo Y, Hill JC, Hudson K, Lia A, Brun J, Withers SG, Martí M, Biasini E, Santino A, De Rosa M, Milani M, Modenutti CP, Hebert DN, Zitzmann N, Roversi P. Guay KP, et al. Among authors: caputo at. iScience. 2023 Sep 20;26(10):107919. doi: 10.1016/j.isci.2023.107919. eCollection 2023 Oct 20. iScience. 2023. PMID: 37822503 Free PMC article.

2

Crystal polymorphism in fragment-based lead discovery of ligands of the catalytic domain of UGGT, the glycoprotein folding quality control checkpoint.

Caputo AT, Ibba R, Le Cornu JD, Darlot B, Hensen M, Lipp CB, Marcianò G, Vasiljević S, Zitzmann N, Roversi P. Caputo AT, et al. Front Mol Biosci. 2022 Dec 14;9:960248. doi: 10.3389/fmolb.2022.960248. eCollection 2022. Front Mol Biosci. 2022. PMID: 36589243 Free PMC article.

3

Enhancing PET Degrading Enzymes: A Combinatory Approach.

Joho Y, Royan S, Caputo AT, Newton S, Peat TS, Newman J, Jackson C, Ardevol A. Joho Y, et al. Among authors: caputo at. Chembiochem. 2024 May 17;25(10):e202400084. doi: 10.1002/cbic.202400084. Epub 2024 May 2. Chembiochem. 2024. PMID: 38584134

4

Ancestral Sequence Reconstruction Identifies Structural Changes Underlying the Evolution of Ideonella sakaiensis PETase and Variants with Improved Stability and Activity.

Joho Y, Vongsouthi V, Spence MA, Ton J, Gomez C, Tan LL, Kaczmarski JA, Caputo AT, Royan S, Jackson CJ, Ardevol A. Joho Y, et al. Among authors: caputo at. Biochemistry. 2023 Jan 17;62(2):437-450. doi: 10.1021/acs.biochem.2c00323. Epub 2022 Aug 11. Biochemistry. 2023. PMID: 35951410

5

Over the rainbow: structural characterization of the chromoproteins gfasPurple, amilCP, spisPink and eforRed.

Ahmed FH, Caputo AT, French NG, Peat TS, Whitfield J, Warden AC, Newman J, Scott C. Ahmed FH, et al. Among authors: caputo at. Acta Crystallogr D Struct Biol. 2022 May 1;78(Pt 5):599-612. doi: 10.1107/S2059798322002625. Epub 2022 Apr 8. Acta Crystallogr D Struct Biol. 2022. PMID: 35503208 Free PMC article.

6

Structure-guided selection of puromycin N-acetyltransferase mutants with enhanced selection stringency for deriving mammalian cell lines expressing recombinant proteins.

Caputo AT, Eder OM, Bereznakova H, Pothuis H, Ardevol A, Newman J, Nuttall S, Peat TS, Adams TE. Caputo AT, et al. Sci Rep. 2021 Mar 4;11(1):5247. doi: 10.1038/s41598-021-84551-9. Sci Rep. 2021. PMID: 33664348 Free PMC article.

7

Molecular characterisation of ILRUN, a novel inhibitor of proinflammatory and antimicrobial cytokines.

Ambrose RL, Brice AM, Caputo AT, Alexander MR, Tribolet L, Liu YC, Adams TE, Bean AGD, Stewart CR. Ambrose RL, et al. Among authors: caputo at. Heliyon. 2020 Jun 3;6(6):e04115. doi: 10.1016/j.heliyon.2020.e04115. eCollection 2020 Jun. Heliyon. 2020. PMID: 32518853 Free PMC article.

8

Targeting Endoplasmic Reticulum α-Glucosidase I with a Single-Dose Iminosugar Treatment Protects against Lethal Influenza and Dengue Virus Infections.

Warfield KL, Alonzi DS, Hill JC, Caputo AT, Roversi P, Kiappes JL, Sheets N, Duchars M, Dwek RA, Biggins J, Barnard D, Shresta S, Treston AM, Zitzmann N. Warfield KL, et al. Among authors: caputo at. J Med Chem. 2020 Apr 23;63(8):4205-4214. doi: 10.1021/acs.jmedchem.0c00067. Epub 2020 Apr 15. J Med Chem. 2020. PMID: 32227946

9

Structural Insights into the Broad-Spectrum Antiviral Target Endoplasmic Reticulum Alpha-Glucosidase II.

Caputo AT, Alonzi DS, Kiappes JL, Struwe WB, Cross A, Basu S, Darlot B, Roversi P, Zitzmann N. Caputo AT, et al. Adv Exp Med Biol. 2018;1062:265-276. doi: 10.1007/978-981-10-8727-1_19. Adv Exp Med Biol. 2018. PMID: 29845539 Review.

10

ToP-DNJ, a Selective Inhibitor of Endoplasmic Reticulum α-Glucosidase II Exhibiting Antiflaviviral Activity.

Kiappes JL, Hill ML, Alonzi DS, Miller JL, Iwaki R, Sayce AC, Caputo AT, Kato A, Zitzmann N. Kiappes JL, et al. Among authors: caputo at. ACS Chem Biol. 2018 Jan 19;13(1):60-65. doi: 10.1021/acschembio.7b00870. Epub 2017 Dec 5. ACS Chem Biol. 2018. PMID: 29161006 Free PMC article.

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