Thome T - Search Results

1

Single-Nuclei RNA-Sequencing of the Gastrocnemius Muscle in Peripheral Artery Disease.

Pass CG, Palzkill V, Tan J, Kim K, Thome T, Yang Q, Fazzone B, Robinson ST, O'Malley KA, Yue F, Scali ST, Berceli SA, Ryan TE. Pass CG, et al. Among authors: thome t. Circ Res. 2023 Oct 27;133(10):791-809. doi: 10.1161/CIRCRESAHA.123.323161. Epub 2023 Oct 12. Circ Res. 2023. PMID: 37823262 Free PMC article.

2

Uremic metabolites impair skeletal muscle mitochondrial energetics through disruption of the electron transport system and matrix dehydrogenase activity.

Thome T, Salyers ZR, Kumar RA, Hahn D, Berru FN, Ferreira LF, Scali ST, Ryan TE. Thome T, et al. Am J Physiol Cell Physiol. 2019 Oct 1;317(4):C701-C713. doi: 10.1152/ajpcell.00098.2019. Epub 2019 Jul 10. Am J Physiol Cell Physiol. 2019. PMID: 31291144 Free PMC article.

3

Chronic kidney disease exacerbates ischemic limb myopathy in mice via altered mitochondrial energetics.

Berru FN, Gray SE, Thome T, Kumar RA, Salyers ZR, Coleman M, Dennis Le, O'Malley K, Ferreira LF, Berceli SA, Scali ST, Ryan TE. Berru FN, et al. Among authors: thome t. Sci Rep. 2019 Oct 29;9(1):15547. doi: 10.1038/s41598-019-52107-7. Sci Rep. 2019. PMID: 31664123 Free PMC article.

4

Impaired muscle mitochondrial energetics is associated with uremic metabolite accumulation in chronic kidney disease.

Thome T, Kumar RA, Burke SK, Khattri RB, Salyers ZR, Kelley RC, Coleman MD, Christou DD, Hepple RT, Scali ST, Ferreira LF, Ryan TE. Thome T, et al. JCI Insight. 2020 Dec 8;6(1):e139826. doi: 10.1172/jci.insight.139826. JCI Insight. 2020. PMID: 33290279 Free PMC article.

5

Tissue-Specific ¹H-NMR Metabolomic Profiling in Mice with Adenine-Induced Chronic Kidney Disease.

Khattri RB, Thome T, Ryan TE. Khattri RB, et al. Among authors: thome t. Metabolites. 2021 Jan 10;11(1):45. doi: 10.3390/metabo11010045. Metabolites. 2021. PMID: 33435175 Free PMC article.

6

Unique Metabolomic Profile of Skeletal Muscle in Chronic Limb Threatening Ischemia.

Khattri RB, Kim K, Thome T, Salyers ZR, O'Malley KA, Berceli SA, Scali ST, Ryan TE. Khattri RB, et al. Among authors: thome t. J Clin Med. 2021 Feb 2;10(3):548. doi: 10.3390/jcm10030548. J Clin Med. 2021. PMID: 33540726 Free PMC article.

7

Skeletal myopathy in CKD: a comparison of adenine-induced nephropathy and 5/6 nephrectomy models in mice.

Kim K, Anderson EM, Thome T, Lu G, Salyers ZR, Cort TA, O'Malley KA, Scali ST, Ryan TE. Kim K, et al. Among authors: thome t. Am J Physiol Renal Physiol. 2021 Jul 1;321(1):F106-F119. doi: 10.1152/ajprenal.00117.2021. Epub 2021 Jun 14. Am J Physiol Renal Physiol. 2021. PMID: 34121452 Free PMC article.

8

Chronic aryl hydrocarbon receptor activity phenocopies smoking-induced skeletal muscle impairment.

Thome T, Miguez K, Willms AJ, Burke SK, Chandran V, de Souza AR, Fitzgerald LF, Baglole C, Anagnostou ME, Bourbeau J, Jagoe RT, Morais JA, Goddard Y, Taivassalo T, Ryan TE, Hepple RT. Thome T, et al. J Cachexia Sarcopenia Muscle. 2022 Feb;13(1):589-604. doi: 10.1002/jcsm.12826. Epub 2021 Nov 1. J Cachexia Sarcopenia Muscle. 2022. PMID: 34725955 Free PMC article.

9

Mitochondrial Bioenergetic and Proteomic Phenotyping Reveals Organ-Specific Consequences of Chronic Kidney Disease in Mice.

Thome T, Coleman MD, Ryan TE. Thome T, et al. Cells. 2021 Nov 24;10(12):3282. doi: 10.3390/cells10123282. Cells. 2021. PMID: 34943790 Free PMC article.

10

Interventional- and amputation-stage muscle proteomes in the chronically threatened ischemic limb.

Ryan TE, Kim K, Scali ST, Berceli SA, Thome T, Salyers ZR, O'Malley KA, Green TD, Karnekar R, Fisher-Wellman KH, Yamaguchi DJ, McClung JM. Ryan TE, et al. Among authors: thome t. Clin Transl Med. 2022 Jan;12(1):e658. doi: 10.1002/ctm2.658. Clin Transl Med. 2022. PMID: 35073463 Free PMC article.

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