Stites E - Search Results

1

Theoretical analysis reveals a role for RAF conformational autoinhibition in paradoxical activation.

Mendiratta G, Stites E. Mendiratta G, et al. Among authors: stites e. Elife. 2023 Oct 12;12:e82739. doi: 10.7554/eLife.82739. Elife. 2023. PMID: 37823369 Free PMC article.

2

Cancer gene mutation frequencies for the U.S. population.

Mendiratta G, Ke E, Aziz M, Liarakos D, Tong M, Stites EC. Mendiratta G, et al. Among authors: stites ec. Nat Commun. 2021 Oct 13;12(1):5961. doi: 10.1038/s41467-021-26213-y. Nat Commun. 2021. PMID: 34645806 Free PMC article.

3

How often is each gene mutated within the cancer patient population?

Mendiratta G, Jones MK, Stites EC. Mendiratta G, et al. Mol Cell Oncol. 2022 May 1;9(1):2065176. doi: 10.1080/23723556.2022.2065176. eCollection 2022. Mol Cell Oncol. 2022. PMID: 35529901 Free PMC article.

4

Systems modeling of oncogenic G-protein and GPCR signaling reveals unexpected differences in downstream pathway activation.

Trogdon M, Abbott K, Arang N, Lande K, Kaur N, Tong M, Bakhoum M, Gutkind JS, Stites EC. Trogdon M, et al. Among authors: stites ec. NPJ Syst Biol Appl. 2024 Jul 16;10(1):75. doi: 10.1038/s41540-024-00400-1. NPJ Syst Biol Appl. 2024. PMID: 39013872 Free PMC article.

5

Mathematical Modeling to Study KRAS Mutant-Specific Responses to Pathway Inhibition.

Stites EC. Stites EC. Methods Mol Biol. 2021;2262:311-321. doi: 10.1007/978-1-0716-1190-6_19. Methods Mol Biol. 2021. PMID: 33977486 Free PMC article.

6

Identification of RAS mutant biomarkers for EGFR inhibitor sensitivity using a systems biochemical approach.

McFall T, Stites EC. McFall T, et al. Cell Rep. 2021 Dec 14;37(11):110096. doi: 10.1016/j.celrep.2021.110096. Cell Rep. 2021. PMID: 34910921 Free PMC article.

7

Computational Random Mutagenesis to Investigate RAS Mutant Signaling.

Stites EC. Stites EC. Methods Mol Biol. 2023;2634:329-335. doi: 10.1007/978-1-0716-3008-2_15. Methods Mol Biol. 2023. PMID: 37074586 Free PMC article.

8

The Abundance of KRAS and RAS Gene Mutations in Cancer.

Stites EC. Stites EC. Methods Mol Biol. 2024;2797:13-22. doi: 10.1007/978-1-0716-3822-4_2. Methods Mol Biol. 2024. PMID: 38570449

9

Modeling cell line-specific recruitment of signaling proteins to the insulin-like growth factor 1 receptor.

Erickson KE, Rukhlenko OS, Shahinuzzaman M, Slavkova KP, Lin YT, Suderman R, Stites EC, Anghel M, Posner RG, Barua D, Kholodenko BN, Hlavacek WS. Erickson KE, et al. Among authors: stites ec. PLoS Comput Biol. 2019 Jan 17;15(1):e1006706. doi: 10.1371/journal.pcbi.1006706. eCollection 2019 Jan. PLoS Comput Biol. 2019. PMID: 30653502 Free PMC article.

10

A systems mechanism for KRAS mutant allele-specific responses to targeted therapy.

McFall T, Diedrich JK, Mengistu M, Littlechild SL, Paskvan KV, Sisk-Hackworth L, Moresco JJ, Shaw AS, Stites EC. McFall T, et al. Sci Signal. 2019 Sep 24;12(600):eaaw8288. doi: 10.1126/scisignal.aaw8288. Sci Signal. 2019. PMID: 31551296 Free PMC article.

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