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Multi-omic analysis of the cardiac cellulome defines a vascular contribution to cardiac diastolic dysfunction in obese female mice.
Dona MSI, Hsu I, Meuth AI, Brown SM, Bailey CA, Aragonez CG, Russell JJ, Krstevski C, Aroor AR, Chandrasekar B, Martinez-Lemus LA, DeMarco VG, Grisanti LA, Jaffe IZ, Pinto AR, Bender SB. Dona MSI, et al. Among authors: demarco vg. Basic Res Cardiol. 2023 Mar 29;118(1):11. doi: 10.1007/s00395-023-00983-6. Basic Res Cardiol. 2023. PMID: 36988733 Free PMC article.
Endothelial cell-specific mineralocorticoid receptor activation promotes diastolic dysfunction in diet-induced obese male mice.
Aroor A, DeMarco VG, Whaley-Connell AT, Jia G, Yang Y, Sharma N, Naz H, Hans C, Hayden MR, Hill MA, Sowers JR, Manrique-Acevedo C, Lastra G. Aroor A, et al. Among authors: demarco vg. Am J Physiol Regul Integr Comp Physiol. 2023 Jan 1;324(1):R90-R101. doi: 10.1152/ajpregu.00274.2021. Epub 2022 Nov 28. Am J Physiol Regul Integr Comp Physiol. 2023. PMID: 36440901 Free PMC article.
Cystamine reduces vascular stiffness in Western diet-fed female mice.
Ramirez-Perez FI, Cabral-Amador FJ, Whaley-Connell AT, Aroor AR, Morales-Quinones M, Woodford ML, Ghiarone T, Ferreira-Santos L, Jurrissen TJ, Manrique-Acevedo CM, Jia G, DeMarco VG, Padilla J, Martinez-Lemus LA, Lastra G. Ramirez-Perez FI, et al. Among authors: demarco vg. Am J Physiol Heart Circ Physiol. 2022 Feb 1;322(2):H167-H180. doi: 10.1152/ajpheart.00431.2021. Epub 2021 Dec 10. Am J Physiol Heart Circ Physiol. 2022. PMID: 34890280 Free PMC article.
The SGLT2 inhibitor Empagliflozin attenuates interleukin-17A-induced human aortic smooth muscle cell proliferation and migration by targeting TRAF3IP2/ROS/NLRP3/Caspase-1-dependent IL-1β and IL-18 secretion.
Sukhanov S, Higashi Y, Yoshida T, Mummidi S, Aroor AR, Jeffrey Russell J, Bender SB, DeMarco VG, Chandrasekar B. Sukhanov S, et al. Among authors: demarco vg. Cell Signal. 2021 Jan;77:109825. doi: 10.1016/j.cellsig.2020.109825. Epub 2020 Nov 4. Cell Signal. 2021. PMID: 33160017 Free PMC article.
96 results