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A conserved isoleucine in the binding pocket of RIG-I controls immune tolerance to mitochondrial RNA.
de Regt AK, Anand K, Ciupka K, Bender F, Gatterdam K, Putschli B, Fusshöller D, Hilbig D, Kirchhoff A, Hunkler C, Wolter S, Grünewald A, Wallerath C, Schuberth-Wagner C, Ludwig J, Paeschke K, Bartok E, Hagelueken G, Hartmann G, Zillinger T, Geyer M, Schlee M. de Regt AK, et al. Among authors: schlee m. Nucleic Acids Res. 2023 Nov 27;51(21):11893-11910. doi: 10.1093/nar/gkad835. Nucleic Acids Res. 2023. PMID: 37831086 Free PMC article.
Identification of Epstein-Barr virus (EBV) nuclear antigen 2 (EBNA2) target proteins by proteome analysis: activation of EBNA2 in conditionally immortalized B cells reflects early events after infection of primary B cells by EBV.
Schlee M, Krug T, Gires O, Zeidler R, Hammerschmidt W, Mailhammer R, Laux G, Sauer G, Lovric J, Bornkamm GW. Schlee M, et al. J Virol. 2004 Apr;78(8):3941-52. doi: 10.1128/jvi.78.8.3941-3952.2004. J Virol. 2004. PMID: 15047810 Free PMC article.
c-Myc and Rel/NF-kappaB are the two master transcriptional systems activated in the latency III program of Epstein-Barr virus-immortalized B cells.
Faumont N, Durand-Panteix S, Schlee M, Grömminger S, Schuhmacher M, Hölzel M, Laux G, Mailhammer R, Rosenwald A, Staudt LM, Bornkamm GW, Feuillard J. Faumont N, et al. Among authors: schlee m. J Virol. 2009 May;83(10):5014-27. doi: 10.1128/JVI.02264-08. Epub 2009 Mar 4. J Virol. 2009. PMID: 19264782 Free PMC article.
Active NF-kappaB signalling is a prerequisite for influenza virus infection.
Nimmerjahn F, Dudziak D, Dirmeier U, Hobom G, Riedel A, Schlee M, Staudt LM, Rosenwald A, Behrends U, Bornkamm GW, Mautner J. Nimmerjahn F, et al. Among authors: schlee m. J Gen Virol. 2004 Aug;85(Pt 8):2347-2356. doi: 10.1099/vir.0.79958-0. J Gen Virol. 2004. PMID: 15269376
siRNA and isRNA: two edges of one sword.
Schlee M, Hornung V, Hartmann G. Schlee M, et al. Mol Ther. 2006 Oct;14(4):463-70. doi: 10.1016/j.ymthe.2006.06.001. Epub 2006 Jul 31. Mol Ther. 2006. PMID: 16877044 Free article. Review.
5'-Triphosphate RNA is the ligand for RIG-I.
Hornung V, Ellegast J, Kim S, Brzózka K, Jung A, Kato H, Poeck H, Akira S, Conzelmann KK, Schlee M, Endres S, Hartmann G. Hornung V, et al. Among authors: schlee m. Science. 2006 Nov 10;314(5801):994-7. doi: 10.1126/science.1132505. Epub 2006 Oct 12. Science. 2006. PMID: 17038590
115 results