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A conserved isoleucine in the binding pocket of RIG-I controls immune tolerance to mitochondrial RNA.
Nucleic Acids Res. 2023 Nov 27;51(21):11893-11910. doi: 10.1093/nar/gkad835.
Nucleic Acids Res. 2023.
PMID: 37831086
Free PMC article.
MOV10 Provides Antiviral Activity against RNA Viruses by Enhancing RIG-I-MAVS-Independent IFN Induction.
Cuevas RA, Ghosh A, Wallerath C, Hornung V, Coyne CB, Sarkar SN.
Cuevas RA, et al. Among authors: wallerath c.
J Immunol. 2016 May 1;196(9):3877-86. doi: 10.4049/jimmunol.1501359. Epub 2016 Mar 25.
J Immunol. 2016.
PMID: 27016603
Free PMC article.
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RNA-binding proteins hnRNPM and ELAVL1 promote type-I interferon induction downstream of the nucleic acid sensors cGAS and RIG-I.
Kirchhoff A, Herzner AM, Urban C, Piras A, Düster R, Mahlberg J, Grünewald A, Schlee-Guimarães TM, Ciupka K, Leka P, Bootz RJ, Wallerath C, Hunkler C, de Regt AK, Kümmerer BM, Christensen MH, Schmidt FI, Lee-Kirsch MA, Günther C, Kato H, Bartok E, Hartmann G, Geyer M, Pichlmair A, Schlee M.
Kirchhoff A, et al. Among authors: wallerath c.
EMBO J. 2024 Dec 20. doi: 10.1038/s44318-024-00331-x. Online ahead of print.
EMBO J. 2024.
PMID: 39707025
Free article.
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The PYHIN Protein p205 Regulates the Inflammasome by Controlling Asc Expression.
Ghosh S, Wallerath C, Covarrubias S, Hornung V, Carpenter S, Fitzgerald KA.
Ghosh S, et al. Among authors: wallerath c.
J Immunol. 2017 Nov 1;199(9):3249-3260. doi: 10.4049/jimmunol.1700823. Epub 2017 Sep 20.
J Immunol. 2017.
PMID: 28931603
Free PMC article.
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