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Page 1
A conserved isoleucine in the binding pocket of RIG-I controls immune tolerance to mitochondrial RNA.
de Regt AK, Anand K, Ciupka K, Bender F, Gatterdam K, Putschli B, Fusshöller D, Hilbig D, Kirchhoff A, Hunkler C, Wolter S, Grünewald A, Wallerath C, Schuberth-Wagner C, Ludwig J, Paeschke K, Bartok E, Hagelueken G, Hartmann G, Zillinger T, Geyer M, Schlee M. de Regt AK, et al. Nucleic Acids Res. 2023 Nov 27;51(21):11893-11910. doi: 10.1093/nar/gkad835. Nucleic Acids Res. 2023. PMID: 37831086 Free PMC article.
RNA-binding proteins hnRNPM and ELAVL1 promote type-I interferon induction downstream of the nucleic acid sensors cGAS and RIG-I.
Kirchhoff A, Herzner AM, Urban C, Piras A, Düster R, Mahlberg J, Grünewald A, Schlee-Guimarães TM, Ciupka K, Leka P, Bootz RJ, Wallerath C, Hunkler C, de Regt AK, Kümmerer BM, Christensen MH, Schmidt FI, Lee-Kirsch MA, Günther C, Kato H, Bartok E, Hartmann G, Geyer M, Pichlmair A, Schlee M. Kirchhoff A, et al. Among authors: de regt ak. EMBO J. 2024 Dec 20. doi: 10.1038/s44318-024-00331-x. Online ahead of print. EMBO J. 2024. PMID: 39707025 Free article.
Novel method for determining when a field-collected donor unit is sufficiently full.
Yazer MH, Werneiwski K, Thompson P, Titlestad K, Watkins T, Smith S, Bengtsson J, Brunetta DM, Carlos L, Jenkins D, Salcido J, Ngamsuntikul SG, Taye H, Kinfu A, Tadesse D, Jackson BP, Kutner J, Yokoyama AP, Hess JR, Tuott E, Ilmakunnas M, de Regt AK, Wiebke H, Seltsam A, Braverman M, Compton F, Sutor L, Meledeo MA, Messenger JM, DePasquale M. Yazer MH, et al. Among authors: de regt ak. Transfusion. 2024 May;64 Suppl 2:S27-S33. doi: 10.1111/trf.17722. Epub 2024 Jan 22. Transfusion. 2024. PMID: 38251751
Identification of functional LsrB-like autoinducer-2 receptors.
Pereira CS, de Regt AK, Brito PH, Miller ST, Xavier KB. Pereira CS, et al. Among authors: de regt ak. J Bacteriol. 2009 Nov;191(22):6975-87. doi: 10.1128/JB.00976-09. Epub 2009 Sep 11. J Bacteriol. 2009. PMID: 19749048 Free PMC article.