Xi XX - Search Results

1

Modification of osimertinib to discover new potent EGFR^C797S-TK inhibitors.

Xi XX, Zhao HY, Mao YZ, Xin M, Zhang SQ. Xi XX, et al. Eur J Med Chem. 2023 Dec 5;261:115865. doi: 10.1016/j.ejmech.2023.115865. Epub 2023 Oct 14. Eur J Med Chem. 2023. PMID: 37839342

2

Discovery of potent epidermal growth factor receptor (EGFR) degraders by proteolysis targeting chimera (PROTAC).

Zhang H, Zhao HY, Xi XX, Liu YJ, Xin M, Mao S, Zhang JJ, Lu AX, Zhang SQ. Zhang H, et al. Among authors: xi xx. Eur J Med Chem. 2020 Mar 1;189:112061. doi: 10.1016/j.ejmech.2020.112061. Epub 2020 Jan 14. Eur J Med Chem. 2020. PMID: 31951960

3

Discovery of potent small molecule PROTACs targeting mutant EGFR.

Zhao HY, Yang XY, Lei H, Xi XX, Lu SM, Zhang JJ, Xin M, Zhang SQ. Zhao HY, et al. Among authors: xi xx. Eur J Med Chem. 2020 Dec 15;208:112781. doi: 10.1016/j.ejmech.2020.112781. Epub 2020 Aug 26. Eur J Med Chem. 2020. PMID: 32883633

4

Discovery of Potent PROTACs Targeting EGFR Mutants through the Optimization of Covalent EGFR Ligands.

Zhao HY, Wang HP, Mao YZ, Zhang H, Xin M, Xi XX, Lei H, Mao S, Li DH, Zhang SQ. Zhao HY, et al. Among authors: xi xx. J Med Chem. 2022 Mar 24;65(6):4709-4726. doi: 10.1021/acs.jmedchem.1c01827. Epub 2022 Mar 7. J Med Chem. 2022. PMID: 35254067

5

Identification of benzamides derivatives of norfloxacin as promising microRNA-21 inhibitors via repressing its transcription.

Xi XX, Hei YY, Guo Y, Zhao HY, Xin M, Lu S, Jiang C, Zhang SQ. Xi XX, et al. Bioorg Med Chem. 2022 Jul 15;66:116803. doi: 10.1016/j.bmc.2022.116803. Epub 2022 May 8. Bioorg Med Chem. 2022. PMID: 35561631

6

Design, synthesis and evaluation of new pyrimidine derivatives as EGFR^C797S tyrosine kinase inhibitors.

Mao YZ, Xi XX, Zhao HY, Zhang YL, Zhang SQ. Mao YZ, et al. Among authors: xi xx. Bioorg Med Chem Lett. 2023 Jul 15;91:129381. doi: 10.1016/j.bmcl.2023.129381. Epub 2023 Jun 17. Bioorg Med Chem Lett. 2023. PMID: 37336419

7

Overcoming C797S mutation: The challenges and prospects of the fourth-generation EGFR-TKIs.

Zhao HY, Xi XX, Xin M, Zhang SQ. Zhao HY, et al. Among authors: xi xx. Bioorg Chem. 2022 Nov;128:106057. doi: 10.1016/j.bioorg.2022.106057. Epub 2022 Aug 1. Bioorg Chem. 2022. PMID: 35964503 Review.

8

Design, synthesis, and evaluation of fluoroquinolone derivatives as microRNA-21 small-molecule inhibitors.

Hei YY, Wang S, Xi XX, Wang HP, Guo Y, Xin M, Jiang C, Lu S, Zhang SQ. Hei YY, et al. Among authors: xi xx. J Pharm Anal. 2022 Aug;12(4):653-663. doi: 10.1016/j.jpha.2021.12.008. Epub 2022 Jan 3. J Pharm Anal. 2022. PMID: 36105166 Free PMC article.

9

Predictive potential of preoperative Naples prognostic score-based nomogram model for the prognosis in surgical resected thoracic esophageal squamous cell carcinoma patients: A retrospective cohort study.

Guo XW, Ji L, Xi XX, Zhao WW, Liu YC, Zhou SB, Ji SJ. Guo XW, et al. Among authors: xi xx. Medicine (Baltimore). 2024 May 3;103(18):e38038. doi: 10.1097/MD.0000000000038038. Medicine (Baltimore). 2024. PMID: 38701277 Free PMC article.

10

[A case of stage Ⅲ pneumoconiosis with large shadow by burr-like changes misdiagnosed as lung cancer].

Xi XX, Yue XL, Wang X, Zhang H, Chen YL. Xi XX, et al. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2023 Apr 20;41(4):314-316. doi: 10.3760/cma.j.cn121094-20220505-00232. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2023. PMID: 37248191 Chinese.

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