Xin M - Search Results

1

Modification of osimertinib to discover new potent EGFR^C797S-TK inhibitors.

Xi XX, Zhao HY, Mao YZ, Xin M, Zhang SQ. Xi XX, et al. Among authors: xin m. Eur J Med Chem. 2023 Dec 5;261:115865. doi: 10.1016/j.ejmech.2023.115865. Epub 2023 Oct 14. Eur J Med Chem. 2023. PMID: 37839342

2

Design, synthesis and evaluation of novel 5-phenylpyridin-2(1H)-one derivatives as potent reversible Bruton's tyrosine kinase inhibitors.

Zhao X, Xin M, Huang W, Ren Y, Jin Q, Tang F, Jiang H, Wang Y, Yang J, Mo S, Xiang H. Zhao X, et al. Among authors: xin m. Bioorg Med Chem. 2015 Jan 15;23(2):348-64. doi: 10.1016/j.bmc.2014.11.006. Epub 2014 Nov 10. Bioorg Med Chem. 2015. PMID: 25515957

3

Design, synthesis and antiproliferative activity evaluation of m-(4-morpholinyl-1,3,5-triazin-2-yl)benzamides in vitro.

Wang XM, Xu J, Xin MH, Lu SM, Zhang SQ. Wang XM, et al. Bioorg Med Chem Lett. 2015 Apr 15;25(8):1730-1735. doi: 10.1016/j.bmcl.2015.02.067. Epub 2015 Mar 6. Bioorg Med Chem Lett. 2015. PMID: 25765909

4

Synthesis and antitumor activities evaluation of m-(4-morpholinoquinazolin-2-yl)benzamides in vitro and in vivo.

Wang XM, Xin MH, Xu J, Kang BR, Li Y, Lu SM, Zhang SQ. Wang XM, et al. Eur J Med Chem. 2015;96:382-95. doi: 10.1016/j.ejmech.2015.04.037. Epub 2015 Apr 17. Eur J Med Chem. 2015. PMID: 25911625

5

Pyrrolo[2,3-b]pyridine derivatives as potent Bruton's tyrosine kinase inhibitors.

Zhao X, Huang W, Wang Y, Xin M, Jin Q, Cai J, Tang F, Zhao Y, Xiang H. Zhao X, et al. Among authors: xin m. Bioorg Med Chem. 2015 Aug 1;23(15):4344-4353. doi: 10.1016/j.bmc.2015.06.023. Epub 2015 Jun 17. Bioorg Med Chem. 2015. PMID: 26169764

6

Modification of N-(6-(2-methoxy-3-(4-fluorophenylsulfonamido)pyridin-5-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)acetamide as PI3Ks inhibitor by replacement of the acetamide group with alkylurea.

Wang XM, Mao S, Cao L, Xie XX, Xin MH, Lian JF, Cao YX, Zhang SQ. Wang XM, et al. Bioorg Med Chem. 2015 Sep 1;23(17):5662-71. doi: 10.1016/j.bmc.2015.07.017. Epub 2015 Jul 17. Bioorg Med Chem. 2015. PMID: 26210161

7

Discovery of thieno[3,2-c]pyridin-4-amines as novel Bruton's tyrosine kinase (BTK) inhibitors.

Zhao X, Xin M, Wang Y, Huang W, Jin Q, Tang F, Wu G, Zhao Y, Xiang H. Zhao X, et al. Among authors: xin m. Bioorg Med Chem. 2015 Sep 1;23(17):6059-68. doi: 10.1016/j.bmc.2015.05.043. Epub 2015 May 31. Bioorg Med Chem. 2015. PMID: 26277759

8

Synthesis and anticancer effects evaluation of 1-alkyl-3-(6-(2-methoxy-3-sulfonylaminopyridin-5-yl)benzo[d]thiazol-2-yl)urea as anticancer agents with low toxicity.

Xie XX, Li H, Wang J, Mao S, Xin MH, Lu SM, Mei QB, Zhang SQ. Xie XX, et al. Bioorg Med Chem. 2015 Oct 1;23(19):6477-85. doi: 10.1016/j.bmc.2015.08.013. Epub 2015 Aug 19. Bioorg Med Chem. 2015. PMID: 26321603

9

Synthesis and biological evaluation of novel 7-substituted 3-(4-phenoxyphenyl)thieno[3,2-c]pyridin-4-amines as potent Bruton's tyrosine kinase (BTK) inhibitors.

Xin M, Zhao X, Huang W, Jin Q, Wu G, Wang Y, Tang F, Xiang H. Xin M, et al. Bioorg Med Chem. 2015 Oct 1;23(19):6250-7. doi: 10.1016/j.bmc.2015.08.039. Epub 2015 Aug 28. Bioorg Med Chem. 2015. PMID: 26344595

10

Synthesis and antitumor activity evaluation of PI3K inhibitors containing 3-substituted quinazolin-4(3H)-one moiety.

Zhang H, Xin MH, Xie XX, Mao S, Zuo SJ, Lu SM, Zhang SQ. Zhang H, et al. Bioorg Med Chem. 2015 Dec 15;23(24):7765-76. doi: 10.1016/j.bmc.2015.11.027. Epub 2015 Nov 22. Bioorg Med Chem. 2015. PMID: 26652969

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