Zhang SQ - Search Results

1

Modification of osimertinib to discover new potent EGFR^C797S-TK inhibitors.

Xi XX, Zhao HY, Mao YZ, Xin M, Zhang SQ. Xi XX, et al. Among authors: zhang sq. Eur J Med Chem. 2023 Dec 5;261:115865. doi: 10.1016/j.ejmech.2023.115865. Epub 2023 Oct 14. Eur J Med Chem. 2023. PMID: 37839342

2

Synthesis and biological evaluation of N-aryl salicylamides with a hydroxamic acid moiety at 5-position as novel HDAC-EGFR dual inhibitors.

Zuo M, Zheng YW, Lu SM, Li Y, Zhang SQ. Zuo M, et al. Among authors: zhang sq. Bioorg Med Chem. 2012 Jul 15;20(14):4405-12. doi: 10.1016/j.bmc.2012.05.034. Epub 2012 May 29. Bioorg Med Chem. 2012. PMID: 22698782

3

Synthesis and anticancer activity evaluation of a series of [1,2,4]triazolo[1,5-a]pyridinylpyridines in vitro and in vivo.

Wang XM, Xu J, Li YP, Li H, Jiang CS, Yang GD, Lu SM, Zhang SQ. Wang XM, et al. Among authors: zhang sq. Eur J Med Chem. 2013 Sep;67:243-51. doi: 10.1016/j.ejmech.2013.06.052. Epub 2013 Jul 4. Eur J Med Chem. 2013. PMID: 23871904

4

Discovery of 2-aryl-8-hydroxy (or methoxy)-isoquinolin-1(2H)-ones as novel EGFR inhibitor by scaffold hopping.

Kang BR, Shan AL, Li YP, Xu J, Lu SM, Zhang SQ. Kang BR, et al. Among authors: zhang sq. Bioorg Med Chem. 2013 Nov 15;21(22):6956-64. doi: 10.1016/j.bmc.2013.09.027. Epub 2013 Sep 18. Bioorg Med Chem. 2013. PMID: 24094432

5

Discovery of 2-methoxy-3-phenylsulfonamino-5-(quinazolin-6-yl or quinolin-6-yl)benzamides as novel PI3K inhibitors and anticancer agents by bioisostere.

Shao T, Wang J, Chen JG, Wang XM, Li H, Li YP, Li Y, Yang GD, Mei QB, Zhang SQ. Shao T, et al. Among authors: zhang sq. Eur J Med Chem. 2014 Mar 21;75:96-105. doi: 10.1016/j.ejmech.2014.01.053. Epub 2014 Jan 29. Eur J Med Chem. 2014. PMID: 24530495

6

Combination of 2-methoxy-3-phenylsulfonylaminobenzamide and 2-aminobenzothiazole to discover novel anticancer agents.

Li H, Wang XM, Wang J, Shao T, Li YP, Mei QB, Lu SM, Zhang SQ. Li H, et al. Among authors: zhang sq. Bioorg Med Chem. 2014 Jul 15;22(14):3739-48. doi: 10.1016/j.bmc.2014.04.064. Epub 2014 May 15. Bioorg Med Chem. 2014. PMID: 24878359

7

Design, synthesis and antiproliferative activity evaluation of m-(4-morpholinyl-1,3,5-triazin-2-yl)benzamides in vitro.

Wang XM, Xu J, Xin MH, Lu SM, Zhang SQ. Wang XM, et al. Among authors: zhang sq. Bioorg Med Chem Lett. 2015 Apr 15;25(8):1730-1735. doi: 10.1016/j.bmcl.2015.02.067. Epub 2015 Mar 6. Bioorg Med Chem Lett. 2015. PMID: 25765909

8

Synthesis and antitumor activities evaluation of m-(4-morpholinoquinazolin-2-yl)benzamides in vitro and in vivo.

Wang XM, Xin MH, Xu J, Kang BR, Li Y, Lu SM, Zhang SQ. Wang XM, et al. Among authors: zhang sq. Eur J Med Chem. 2015;96:382-95. doi: 10.1016/j.ejmech.2015.04.037. Epub 2015 Apr 17. Eur J Med Chem. 2015. PMID: 25911625

9

Modification of N-(6-(2-methoxy-3-(4-fluorophenylsulfonamido)pyridin-5-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)acetamide as PI3Ks inhibitor by replacement of the acetamide group with alkylurea.

Wang XM, Mao S, Cao L, Xie XX, Xin MH, Lian JF, Cao YX, Zhang SQ. Wang XM, et al. Among authors: zhang sq. Bioorg Med Chem. 2015 Sep 1;23(17):5662-71. doi: 10.1016/j.bmc.2015.07.017. Epub 2015 Jul 17. Bioorg Med Chem. 2015. PMID: 26210161

10

Synthesis and anticancer effects evaluation of 1-alkyl-3-(6-(2-methoxy-3-sulfonylaminopyridin-5-yl)benzo[d]thiazol-2-yl)urea as anticancer agents with low toxicity.

Xie XX, Li H, Wang J, Mao S, Xin MH, Lu SM, Mei QB, Zhang SQ. Xie XX, et al. Among authors: zhang sq. Bioorg Med Chem. 2015 Oct 1;23(19):6477-85. doi: 10.1016/j.bmc.2015.08.013. Epub 2015 Aug 19. Bioorg Med Chem. 2015. PMID: 26321603

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