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In vivo photopharmacology with light-activated opioid drugs.
McClain SP, Ma X, Johnson DA, Johnson CA, Layden AE, Yung JC, Lubejko ST, Livrizzi G, He XJ, Zhou J, Chang-Weinberg J, Ventriglia E, Rizzo A, Levinstein M, Gomez JL, Bonaventura J, Michaelides M, Banghart MR. McClain SP, et al. Among authors: gomez jl. Neuron. 2023 Dec 20;111(24):3926-3940.e10. doi: 10.1016/j.neuron.2023.09.017. Epub 2023 Oct 16. Neuron. 2023. PMID: 37848025 Free PMC article.
Dopamine D2 Receptor Signaling in the Nucleus Accumbens Comprises a Metabolic-Cognitive Brain Interface Regulating Metabolic Components of Glucose Reinforcement.
Michaelides M, Miller ML, DiNieri JA, Gomez JL, Schwartz E, Egervari G, Wang GJ, Mobbs CV, Volkow ND, Hurd YL. Michaelides M, et al. Among authors: gomez jl. Neuropsychopharmacology. 2017 Nov;42(12):2365-2376. doi: 10.1038/npp.2017.112. Epub 2017 Jun 5. Neuropsychopharmacology. 2017. PMID: 28580946 Free PMC article.
Chemogenetics revealed: DREADD occupancy and activation via converted clozapine.
Gomez JL, Bonaventura J, Lesniak W, Mathews WB, Sysa-Shah P, Rodriguez LA, Ellis RJ, Richie CT, Harvey BK, Dannals RF, Pomper MG, Bonci A, Michaelides M. Gomez JL, et al. Science. 2017 Aug 4;357(6350):503-507. doi: 10.1126/science.aan2475. Science. 2017. PMID: 28774929 Free PMC article.
Ultrapotent chemogenetics for research and potential clinical applications.
Magnus CJ, Lee PH, Bonaventura J, Zemla R, Gomez JL, Ramirez MH, Hu X, Galvan A, Basu J, Michaelides M, Sternson SM. Magnus CJ, et al. Among authors: gomez jl. Science. 2019 Apr 12;364(6436):eaav5282. doi: 10.1126/science.aav5282. Epub 2019 Mar 14. Science. 2019. PMID: 30872534 Free PMC article.
High-potency ligands for DREADD imaging and activation in rodents and monkeys.
Bonaventura J, Eldridge MAG, Hu F, Gomez JL, Sanchez-Soto M, Abramyan AM, Lam S, Boehm MA, Ruiz C, Farrell MR, Moreno A, Galal Faress IM, Andersen N, Lin JY, Moaddel R, Morris PJ, Shi L, Sibley DR, Mahler SV, Nabavi S, Pomper MG, Bonci A, Horti AG, Richmond BJ, Michaelides M. Bonaventura J, et al. Among authors: gomez jl. Nat Commun. 2019 Oct 11;10(1):4627. doi: 10.1038/s41467-019-12236-z. Nat Commun. 2019. PMID: 31604917 Free PMC article.
Pharmacological and behavioral divergence of ketamine enantiomers: implications for abuse liability.
Bonaventura J, Lam S, Carlton M, Boehm MA, Gomez JL, Solís O, Sánchez-Soto M, Morris PJ, Fredriksson I, Thomas CJ, Sibley DR, Shaham Y, Zarate CA Jr, Michaelides M. Bonaventura J, et al. Among authors: gomez jl. Mol Psychiatry. 2021 Nov;26(11):6704-6722. doi: 10.1038/s41380-021-01093-2. Epub 2021 Apr 15. Mol Psychiatry. 2021. PMID: 33859356 Free PMC article.
Time will tell. Reply to "Comments to pharmacological and behavioral divergence of ketamine enantiomers by Jordi Bonaventura et al." by Chen et al.
Bonaventura J, Lam S, Carlton M, Boehm M, Gomez JL, Solís O, Sánchez-Soto M, Morris PJ, Fredriksson I, Thomas CJ, Sibley DR, Shaham Y, Zarate CA Jr, Michaelides M. Bonaventura J, et al. Among authors: gomez jl. Mol Psychiatry. 2022 Apr;27(4):1863-1865. doi: 10.1038/s41380-022-01480-3. Epub 2022 Feb 22. Mol Psychiatry. 2022. PMID: 35194167 Free PMC article. No abstract available.
257 results