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Page 1
Design of Next-Generation DGAT2 Inhibitor PF-07202954 with Longer Predicted Half-Life.
Filipski KJ, Edmonds DJ, Garnsey MR, Smaltz DJ, Coffman K, Futatsugi K, Lee J, O'Neil SV, Wright A, Nason D, Gosset JR, Orozco CC, Blackler D, Fakhoury G, Gutierrez JA, Perez S, Ross T, Stock I, Tesz G, Dullea R. Filipski KJ, et al. Among authors: blackler d. ACS Med Chem Lett. 2023 Oct 2;14(10):1427-1433. doi: 10.1021/acsmedchemlett.3c00330. eCollection 2023 Oct 12. ACS Med Chem Lett. 2023. PMID: 37849537 Free PMC article.
A null variant in the apolipoprotein L3 gene is associated with non-diabetic nephropathy.
Skorecki KL, Lee JH, Langefeld CD, Rosset S, Tzur S, Wasser WG, Shemer R, Hawkins GA, Divers J, Parekh RS, Li M, Sampson MG, Kretzler M, Pollak MR, Shah S, Blackler D, Nichols B, Wilmot M, Alper SL, Freedman BI, Friedman DJ. Skorecki KL, et al. Among authors: blackler d. Nephrol Dial Transplant. 2018 Feb 1;33(2):323-330. doi: 10.1093/ndt/gfw451. Nephrol Dial Transplant. 2018. PMID: 28339911 Free PMC article.
Innate immunity pathways regulate the nephropathy gene Apolipoprotein L1.
Nichols B, Jog P, Lee JH, Blackler D, Wilmot M, D'Agati V, Markowitz G, Kopp JB, Alper SL, Pollak MR, Friedman DJ. Nichols B, et al. Among authors: blackler d. Kidney Int. 2015 Feb;87(2):332-42. doi: 10.1038/ki.2014.270. Epub 2014 Aug 6. Kidney Int. 2015. PMID: 25100047 Free PMC article.