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A conserved switch to less catalytically active Polycomb repressive complexes in non-dividing cells.
McCole R, Nolan J, Reck DM, Monger C, Rustichelli S, Conway E, Brien GL, Wang C, Deevy O, Neikes HK, Bashore FM, Mooney A, Flavin R, Vandenberghe E, Flanigan SF, Pasini D, Davidovich C, Vermeulen M, James LI, Healy E, Bracken AP. McCole R, et al. Among authors: bracken ap. Cell Rep. 2025 Jan 11;44(1):115192. doi: 10.1016/j.celrep.2024.115192. Online ahead of print. Cell Rep. 2025. PMID: 39799569 Free article.
PIC-king apart PRC1-mediated repression.
Healy E, Bracken AP. Healy E, et al. Among authors: bracken ap. Trends Genet. 2025 Jan;41(1):4-5. doi: 10.1016/j.tig.2024.10.013. Epub 2024 Nov 20. Trends Genet. 2025. PMID: 39572355 Free article.
Macrophage innate training induced by IL-4 and IL-13 activation enhances OXPHOS driven anti-mycobacterial responses.
Lundahl MLE, Mitermite M, Ryan DG, Case S, Williams NC, Yang M, Lynch RI, Lagan E, Lebre FM, Gorman AL, Stojkovic B, Bracken AP, Frezza C, Sheedy FJ, Scanlan EM, O'Neill LAJ, Gordon SV, Lavelle EC. Lundahl MLE, et al. Among authors: bracken ap. Elife. 2022 Sep 29;11:e74690. doi: 10.7554/eLife.74690. Elife. 2022. PMID: 36173104 Free PMC article.
Analytical Validation of a Novel 6-Gene Signature for Prediction of Distant Recurrence in Estrogen Receptor-Positive, HER2-Negative, Early-Stage Breast Cancer.
Loughman T, Barron S, Wang CA, Dynoodt P, Fender B, Lopez-Ruiz C, Stapleton S, Fabre A, Quinn C, Nodin B, Jirström K, Razmara F, O'Grady A, Baird AM, Gray SG, Freixo A, Moelans CB, van Diest PJ, Duffy MJ, O'Leary D, Crown J, Bracken AP, Gallagher WM. Loughman T, et al. Among authors: bracken ap. Clin Chem. 2022 Jun 1;68(6):837-847. doi: 10.1093/clinchem/hvac028. Clin Chem. 2022. PMID: 35312747
Simultaneous disruption of PRC2 and enhancer function underlies histone H3.3-K27M oncogenic activity in human hindbrain neural stem cells.
Brien GL, Bressan RB, Monger C, Gannon D, Lagan E, Doherty AM, Healy E, Neikes H, Fitzpatrick DJ, Deevy O, Grant V, Marqués-Torrejón MA, Alfazema N, Pollard SM, Bracken AP. Brien GL, et al. Among authors: bracken ap. Nat Genet. 2021 Aug;53(8):1221-1232. doi: 10.1038/s41588-021-00897-w. Epub 2021 Jul 22. Nat Genet. 2021. PMID: 34294917
Prognostic value of the 6-gene OncoMasTR test in hormone receptor-positive HER2-negative early-stage breast cancer: Comparative analysis with standard clinicopathological factors.
Lynch SM, Russell NM, Barron S, Wang CA, Loughman T, Dynoodt P, Fender B, Lopez-Ruiz C, O'Grady A, Sheehan KM, Fay J, Amberger-Murphy V, Saha A, Klinger R, Gonzalez CA, Al-Attar N, Rahman A, O'Leary D, Lanigan FT, Bracken AP, Crown J, Kelly CM, O'Connor DP, Gallagher WM. Lynch SM, et al. Among authors: bracken ap. Eur J Cancer. 2021 Jul;152:78-89. doi: 10.1016/j.ejca.2021.04.016. Epub 2021 Jun 2. Eur J Cancer. 2021. PMID: 34090143 Free article.
54 results