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A conserved switch to less catalytically active Polycomb repressive complexes in non-dividing cells.
McCole R, Nolan J, Reck DM, Monger C, Rustichelli S, Conway E, Brien GL, Wang C, Deevy O, Neikes HK, Bashore FM, Mooney A, Flavin R, Vandenberghe E, Flanigan SF, Pasini D, Davidovich C, Vermeulen M, James LI, Healy E, Bracken AP. McCole R, et al. Among authors: pasini d. Cell Rep. 2025 Jan 11;44(1):115192. doi: 10.1016/j.celrep.2024.115192. Online ahead of print. Cell Rep. 2025. PMID: 39799569 Free article.
Differential activity of MAPK signalling defines fibroblast subtypes in pancreatic cancer.
Veghini L, Pasini D, Fang R, Delfino P, Filippini D, Neander C, Vicentini C, Fiorini E, Lupo F, D'Agosto SL, Carbone C, Agostini A, Piro G, Rosa D, Bevere M, Markus P, Behrens D, Luchini C, Lawlor RT, Scarpa A, Biffi G, Cheung PF, Siveke JT, Corbo V. Veghini L, et al. Among authors: pasini d. Nat Commun. 2024 Dec 3;15(1):10534. doi: 10.1038/s41467-024-54975-8. Nat Commun. 2024. PMID: 39627211 Free PMC article.
Polycomb group protein Mel18 inhibits hematopoietic stem cell self-renewal through repressing the transcription of self-renewal and proliferation genes.
Cai W, Liu X, Barajas S, Xiao S, Vemula S, Chen H, Yang Y, Bochers C, Henley D, Liu S, Jia Y, Hong M, Mays TM, Capitano ML, Liu H, Ji P, Gao Z, Pasini D, Wan J, Yue F, Platanias LC, Xi R, Chen S, Liu Y. Cai W, et al. Among authors: pasini d. Leukemia. 2024 Nov 19. doi: 10.1038/s41375-024-02462-w. Online ahead of print. Leukemia. 2024. PMID: 39562720
WNT Oncogenic Transcription Requires MYC Suppression of Lysosomal Activity and EPCAM Stabilization in Gastric Tumors.
Mulè P, Fernandez-Perez D, Amato S, Manganaro D, Oldani P, Brandini S, Diaferia G, Cuomo A, Recordati C, Soriani C, Dondi A, Zanotti M, Rustichelli S, Bisso A, Pece S, Rodighiero S, Natoli G, Amati B, Ferrari KJ, Chiacchiera F, Pasini D. Mulè P, et al. Among authors: pasini d. Gastroenterology. 2024 Oct;167(5):903-918. doi: 10.1053/j.gastro.2024.06.029. Epub 2024 Jul 5. Gastroenterology. 2024. PMID: 38971196 Free article.
220 results