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Glucagon Receptor Antagonism Improves Glucose Metabolism and Cardiac Function by Promoting AMP-Mediated Protein Kinase in Diabetic Mice.
Sharma AX, Quittner-Strom EB, Lee Y, Johnson JA, Martin SA, Yu X, Li J, Lu J, Cai Z, Chen S, Wang MY, Zhang Y, Pearson MJ, Dorn AC, McDonald JG, Gordillo R, Yan H, Thai D, Wang ZV, Unger RH, Holland WL. Sharma AX, et al. Among authors: wang my, wang zv. Cell Rep. 2018 Feb 13;22(7):1760-1773. doi: 10.1016/j.celrep.2018.01.065. Cell Rep. 2018. PMID: 29444429 Free PMC article.
Dermal adipose tissue has high plasticity and undergoes reversible dedifferentiation in mice.
Zhang Z, Shao M, Hepler C, Zi Z, Zhao S, An YA, Zhu Y, Ghaben AL, Wang MY, Li N, Onodera T, Joffin N, Crewe C, Zhu Q, Vishvanath L, Kumar A, Xing C, Wang QA, Gautron L, Deng Y, Gordillo R, Kruglikov I, Kusminski CM, Gupta RK, Scherer PE. Zhang Z, et al. Among authors: wang my, wang qa. J Clin Invest. 2019 Dec 2;129(12):5327-5342. doi: 10.1172/JCI130239. J Clin Invest. 2019. PMID: 31503545 Free PMC article.
Adiponectin preserves metabolic fitness during aging.
Li N, Zhao S, Zhang Z, Zhu Y, Gliniak CM, Vishvanath L, An YA, Wang MY, Deng Y, Zhu Q, Shan B, Sherwood A, Onodera T, Oz OK, Gordillo R, Gupta RK, Liu M, Horvath TL, Dixit VD, Scherer PE. Li N, et al. Among authors: wang my. Elife. 2021 Apr 27;10:e65108. doi: 10.7554/eLife.65108. Elife. 2021. PMID: 33904399 Free PMC article.
Adipocyte iron levels impinge on a fat-gut crosstalk to regulate intestinal lipid absorption and mediate protection from obesity.
Zhang Z, Funcke JB, Zi Z, Zhao S, Straub LG, Zhu Y, Zhu Q, Crewe C, An YA, Chen S, Li N, Wang MY, Ghaben AL, Lee C, Gautron L, Engelking LJ, Raj P, Deng Y, Gordillo R, Kusminski CM, Scherer PE. Zhang Z, et al. Among authors: wang my. Cell Metab. 2021 Aug 3;33(8):1624-1639.e9. doi: 10.1016/j.cmet.2021.06.001. Epub 2021 Jun 25. Cell Metab. 2021. PMID: 34174197 Free PMC article.
Protective roles of adiponectin and molecular signatures of HNF4α and PPARα as downstream targets of adiponectin in pancreatic β cells.
Onodera T, Kim DS, Ye R, Wang MY, Chen S, Field BC, Straub L, Sun XN, Li C, Lee C, Paredes M, Crewe C, Zhao S, Kusminski CM, Gordillo R, Scherer PE. Onodera T, et al. Among authors: wang my. Mol Metab. 2023 Dec;78:101821. doi: 10.1016/j.molmet.2023.101821. Epub 2023 Oct 6. Mol Metab. 2023. PMID: 37806486 Free PMC article.
Endogenous renal adiponectin drives gluconeogenesis through enhancing pyruvate and fatty acid utilization.
Onodera T, Wang MY, Rutkowski JM, Deja S, Chen S, Balzer MS, Kim DS, Sun X, An YA, Field BC, Lee C, Matsuo EI, Mizerska M, Sanjana I, Fujiwara N, Kusminski CM, Gordillo R, Gautron L, Marciano DK, Hu MC, Burgess SC, Susztak K, Moe OW, Scherer PE. Onodera T, et al. Among authors: wang my. Nat Commun. 2023 Oct 17;14(1):6531. doi: 10.1038/s41467-023-42188-4. Nat Commun. 2023. PMID: 37848446 Free PMC article.
Hyperleptinemia contributes to antipsychotic drug-associated obesity and metabolic disorders.
Zhao S, Lin Q, Xiong W, Li L, Straub L, Zhang D, Zapata R, Zhu Q, Sun XN, Zhang Z, Funcke JB, Li C, Chen S, Zhu Y, Jiang N, Li G, Xu Z, Wyler SC, Wang MY, Bai J, Han X, Kusminski CM, Zhang N, An Z, Elmquist JK, Osborn O, Liu C, Scherer PE. Zhao S, et al. Among authors: wang my. Sci Transl Med. 2023 Nov 22;15(723):eade8460. doi: 10.1126/scitranslmed.ade8460. Epub 2023 Nov 22. Sci Transl Med. 2023. PMID: 37992151
2,084 results