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Page 1
Surfaceome analysis of extracellular vesicles from senescent cells uncovers uptake repressor DPP4.
Meng Q, Chen C, Yang N, Gololobova O, Shi C, Dunn CA, Rossi M, Martindale JL, Basisty N, Ding J, Delannoy M, Basu S, Mazan-Mamczarz K, Shin CH, Yang JH, Johnson PF, Witwer KW, Biragyn A, Sen P, Abdelmohsen K, De S, Gorospe M. Meng Q, et al. Among authors: dunn ca. Proc Natl Acad Sci U S A. 2023 Oct 24;120(43):e2219801120. doi: 10.1073/pnas.2219801120. Epub 2023 Oct 20. Proc Natl Acad Sci U S A. 2023. PMID: 37862381 Free PMC article.
Proteomes of primary skin fibroblasts from healthy individuals reveal altered cell responses across the life span.
Tsitsipatis D, Martindale JL, Ubaida-Mohien C, Lyashkov A, Yanai H, Kashyap A, Shin CH, Herman AB, Ji E, Yang JH, Munk R, Dunn C, Lukyanenko Y, Yang X, Chia CW, Karikkineth AC, Zukley L, D'Agostino J, Kaileh M, Cui CY, Beerman I, Ferrucci L, Gorospe M. Tsitsipatis D, et al. Aging Cell. 2022 May;21(5):e13609. doi: 10.1111/acel.13609. Epub 2022 Apr 15. Aging Cell. 2022. PMID: 35429111 Free PMC article.
Gene body DNA hydroxymethylation restricts the magnitude of transcriptional changes during aging.
Occean JR, Yang N, Sun Y, Dawkins MS, Munk R, Belair C, Dar S, Anerillas C, Wang L, Shi C, Dunn C, Bernier M, Price NL, Kim JS, Cui CY, Fan J, Bhattacharyya M, De S, Maragkakis M, deCabo R, Sidoli S, Sen P. Occean JR, et al. bioRxiv [Preprint]. 2024 Jul 3:2023.02.15.528714. doi: 10.1101/2023.02.15.528714. bioRxiv. 2024. Update in: Nat Commun. 2024 Jul 28;15(1):6357. doi: 10.1038/s41467-024-50725-y PMID: 36824863 Free PMC article. Updated. Preprint.
DNA methylation signatures reveal that distinct combinations of transcription factors specify human immune cell epigenetic identity.
Roy R, Ramamoorthy S, Shapiro BD, Kaileh M, Hernandez D, Sarantopoulou D, Arepalli S, Boller S, Singh A, Bektas A, Kim J, Moore AZ, Tanaka T, McKelvey J, Zukley L, Nguyen C, Wallace T, Dunn C, Wersto R, Wood W, Piao Y, Becker KG, Coletta C, De S, Sen JM, Battle A, Weng NP, Grosschedl R, Ferrucci L, Sen R. Roy R, et al. Immunity. 2021 Nov 9;54(11):2465-2480.e5. doi: 10.1016/j.immuni.2021.10.001. Epub 2021 Oct 26. Immunity. 2021. PMID: 34706222 Free PMC article.
Epigenetic signature of human immune aging in the GESTALT study.
Roy R, Kuo PL, Candia J, Sarantopoulou D, Ubaida-Mohien C, Hernandez D, Kaileh M, Arepalli S, Singh A, Bektas A, Kim J, Moore AZ, Tanaka T, McKelvey J, Zukley L, Nguyen C, Wallace T, Dunn C, Wood W, Piao Y, Coletta C, De S, Sen J, Weng NP, Sen R, Ferrucci L. Roy R, et al. Elife. 2023 Aug 17;12:e86136. doi: 10.7554/eLife.86136. Elife. 2023. PMID: 37589453 Free PMC article.
SARS-CoV-2 infection establishes a stable and age-independent CD8+ T cell response against a dominant nucleocapsid epitope using restricted T cell receptors.
Choy C, Chen J, Li J, Gallagher DT, Lu J, Wu D, Zou A, Hemani H, Baptiste BA, Wichmann E, Yang Q, Ciffelo J, Yin R, McKelvy J, Melvin D, Wallace T, Dunn C, Nguyen C, Chia CW, Fan J, Ruffolo J, Zukley L, Shi G, Amano T, An Y, Meirelles O, Wu WW, Chou CK, Shen RF, Willis RA, Ko MSH, Liu YT, De S, Pierce BG, Ferrucci L, Egan J, Mariuzza R, Weng NP. Choy C, et al. Nat Commun. 2023 Oct 23;14(1):6725. doi: 10.1038/s41467-023-42430-z. Nat Commun. 2023. PMID: 37872153 Free PMC article.
Single-extracellular vesicle (EV) analyses validate the use of L1 Cell Adhesion Molecule (L1CAM) as a reliable biomarker of neuron-derived EVs.
Nogueras-Ortiz CJ, Eren E, Yao P, Calzada E, Dunn C, Volpert O, Delgado-Peraza F, Mustapic M, Lyashkov A, Rubio FJ, Vreones M, Cheng L, You Y, Hill AF, Ikezu T, Eitan E, Goetzl EJ, Kapogiannis D. Nogueras-Ortiz CJ, et al. J Extracell Vesicles. 2024 Jun;13(6):e12459. doi: 10.1002/jev2.12459. J Extracell Vesicles. 2024. PMID: 38868956 Free PMC article.
74 results