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A human in vitro neuronal model for studying homeostatic plasticity at the network level.
Yuan X, Puvogel S, van Rhijn JR, Ciptasari U, Esteve-Codina A, Meijer M, Rouschop S, van Hugte EJH, Oudakker A, Schoenmaker C, Frega M, Schubert D, Franke B, Nadif Kasri N. Yuan X, et al. Among authors: schubert d. Stem Cell Reports. 2023 Nov 14;18(11):2222-2239. doi: 10.1016/j.stemcr.2023.09.011. Epub 2023 Oct 19. Stem Cell Reports. 2023. PMID: 37863044 Free PMC article.
SCN1A-deficient excitatory neuronal networks display mutation-specific phenotypes.
van Hugte EJH, Lewerissa EI, Wu KM, Scheefhals N, Parodi G, van Voorst TW, Puvogel S, Kogo N, Keller JM, Frega M, Schubert D, Schelhaas HJ, Verhoeven J, Majoie M, van Bokhoven H, Nadif Kasri N. van Hugte EJH, et al. Among authors: schubert d. Brain. 2023 Dec 1;146(12):5153-5167. doi: 10.1093/brain/awad245. Brain. 2023. PMID: 37467479 Free PMC article.
Impaired GABAergic regulation and developmental immaturity in interneurons derived from the medial ganglionic eminence in the tuberous sclerosis complex.
Scheper M, Sørensen FNF, Ruffolo G, Gaeta A, Lissner LJ, Anink JJ, Korshunova I, Jansen FE, Riney K, van Hecke W, Mühlebner A, Khodosevich K, Schubert D, Palma E, Mills JD, Aronica E. Scheper M, et al. Among authors: schubert d. Acta Neuropathol. 2024 May 7;147(1):80. doi: 10.1007/s00401-024-02737-7. Acta Neuropathol. 2024. PMID: 38714540 Free PMC article.
CACNA1A haploinsufficiency leads to reduced synaptic function and increased intrinsic excitability.
Hommersom MP, Doorn N, Puvogel S, Lewerissa EI, Mordelt A, Ciptasari U, Kampshoff F, Dillen L, van Beusekom E, Oudakker A, Kogo N, Dolga AM, Frega M, Schubert D, van de Warrenburg BPC, Nadif Kasri N, van Bokhoven H. Hommersom MP, et al. Among authors: schubert d. Brain. 2024 Oct 26:awae330. doi: 10.1093/brain/awae330. Online ahead of print. Brain. 2024. PMID: 39460936
713 results