Ryan TA - Search Results

1

Phosphoglycerate kinase is a central leverage point in Parkinson's Disease driven neuronal metabolic deficits.

Kokotos AC, Antoniazzi AM, Unda SR, Ko MS, Park D, Eliezer D, Kaplitt MG, Camilli P, Ryan TA. Kokotos AC, et al. Among authors: ryan ta. bioRxiv [Preprint]. 2023 Oct 10:2023.10.10.561760. doi: 10.1101/2023.10.10.561760. bioRxiv. 2023. Update in: Sci Adv. 2024 Aug 23;10(34):eadn6016. doi: 10.1126/sciadv.adn6016 PMID: 37873141 Free PMC article. Updated. Preprint.

2

iATPSnFR2: A high-dynamic-range fluorescent sensor for monitoring intracellular ATP.

Marvin JS, Kokotos AC, Kumar M, Pulido C, Tkachuk AN, Yao JS, Brown TA, Ryan TA. Marvin JS, et al. Among authors: ryan ta. Proc Natl Acad Sci U S A. 2024 May 21;121(21):e2314604121. doi: 10.1073/pnas.2314604121. Epub 2024 May 15. Proc Natl Acad Sci U S A. 2024. PMID: 38748581 Free PMC article.

3

Phosphoglycerate kinase is a central leverage point in Parkinson's disease-driven neuronal metabolic deficits.

Kokotos AC, Antoniazzi AM, Unda SR, Ko MS, Park D, Eliezer D, Kaplitt MG, De Camilli P, Ryan TA. Kokotos AC, et al. Among authors: ryan ta. Sci Adv. 2024 Aug 23;10(34):eadn6016. doi: 10.1126/sciadv.adn6016. Epub 2024 Aug 21. Sci Adv. 2024. PMID: 39167658 Free PMC article.

4

Parkinson Sac Domain Mutation in Synaptojanin 1 Impairs Clathrin Uncoating at Synapses and Triggers Dystrophic Changes in Dopaminergic Axons.

Cao M, Wu Y, Ashrafi G, McCartney AJ, Wheeler H, Bushong EA, Boassa D, Ellisman MH, Ryan TA, De Camilli P. Cao M, et al. Among authors: ryan ta. Neuron. 2017 Feb 22;93(4):882-896.e5. doi: 10.1016/j.neuron.2017.01.019. Neuron. 2017. PMID: 28231468 Free PMC article.

5

Molecular Tuning of the Axonal Mitochondrial Ca²⁺ Uniporter Ensures Metabolic Flexibility of Neurotransmission.

Ashrafi G, de Juan-Sanz J, Farrell RJ, Ryan TA. Ashrafi G, et al. Among authors: ryan ta. Neuron. 2020 Feb 19;105(4):678-687.e5. doi: 10.1016/j.neuron.2019.11.020. Epub 2019 Dec 17. Neuron. 2020. PMID: 31862210 Free PMC article.

6

Synaptic vesicle pools are a major hidden resting metabolic burden of nerve terminals.

Pulido C, Ryan TA. Pulido C, et al. Among authors: ryan ta. Sci Adv. 2021 Dec 3;7(49):eabi9027. doi: 10.1126/sciadv.abi9027. Epub 2021 Dec 3. Sci Adv. 2021. PMID: 34860552 Free PMC article.

7

GLUT4 Mobilization Supports Energetic Demands of Active Synapses.

Ashrafi G, Wu Z, Farrell RJ, Ryan TA. Ashrafi G, et al. Among authors: ryan ta. Neuron. 2017 Feb 8;93(3):606-615.e3. doi: 10.1016/j.neuron.2016.12.020. Epub 2017 Jan 19. Neuron. 2017. PMID: 28111082 Free PMC article.

8

Glucose metabolism in nerve terminals.

Ashrafi G, Ryan TA. Ashrafi G, et al. Among authors: ryan ta. Curr Opin Neurobiol. 2017 Aug;45:156-161. doi: 10.1016/j.conb.2017.03.007. Epub 2017 Jun 9. Curr Opin Neurobiol. 2017. PMID: 28605677 Free PMC article. Review.

9

Activity-driven local ATP synthesis is required for synaptic function.

Rangaraju V, Calloway N, Ryan TA. Rangaraju V, et al. Among authors: ryan ta. Cell. 2014 Feb 13;156(4):825-35. doi: 10.1016/j.cell.2013.12.042. Cell. 2014. PMID: 24529383 Free PMC article.

10

Parkinson's Disease-Associated LRRK2 Hyperactive Kinase Mutant Disrupts Synaptic Vesicle Trafficking in Ventral Midbrain Neurons.

Pan PY, Li X, Wang J, Powell J, Wang Q, Zhang Y, Chen Z, Wicinski B, Hof P, Ryan TA, Yue Z. Pan PY, et al. Among authors: ryan ta. J Neurosci. 2017 Nov 22;37(47):11366-11376. doi: 10.1523/JNEUROSCI.0964-17.2017. Epub 2017 Oct 20. J Neurosci. 2017. PMID: 29054882 Free PMC article.

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