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Post-ischemic inactivation of HIF prolyl hydroxylases in endothelium promotes maladaptive kidney repair by inducing glycolysis.
Tiwari R, Sharma R, Rajendran G, Borkowski GS, An SY, Schonfeld M, O'Sullivan J, Schipma MJ, Zhou Y, Courbon G, David V, Quaggin SE, Thorp E, Chandel NS, Kapitsinou PP. Tiwari R, et al. Among authors: chandel ns. bioRxiv [Preprint]. 2023 Oct 3:2023.10.03.560700. doi: 10.1101/2023.10.03.560700. bioRxiv. 2023. Update in: J Clin Invest. 2024 Nov 26:e176207. doi: 10.1172/JCI176207 PMID: 37873349 Free PMC article. Updated. Preprint.
A Drosophila model of mitochondrial disease phenotypic heterogeneity.
Granat L, Knorr DY, Ranson DC, Chakrabarty RP, Chandel NS, Bateman JM. Granat L, et al. Among authors: chandel ns. Biol Open. 2024 Feb 15;13(2):bio060278. doi: 10.1242/bio.060278. Epub 2024 Feb 28. Biol Open. 2024. PMID: 38304969 Free PMC article.
Oxidative phosphorylation selectively orchestrates tissue macrophage homeostasis.
Wculek SK, Heras-Murillo I, Mastrangelo A, Mañanes D, Galán M, Miguel V, Curtabbi A, Barbas C, Chandel NS, Enríquez JA, Lamas S, Sancho D. Wculek SK, et al. Among authors: chandel ns. Immunity. 2023 Mar 14;56(3):516-530.e9. doi: 10.1016/j.immuni.2023.01.011. Epub 2023 Feb 3. Immunity. 2023. PMID: 36738738 Free article.
Myeloid cell-derived creatine in the hypoxic niche promotes glioblastoma growth.
Rashidi A, Billingham LK, Zolp A, Chia TY, Silvers C, Katz JL, Park CH, Delay S, Boland L, Geng Y, Markwell SM, Dmello C, Arrieta VA, Zilinger K, Jacob IM, Lopez-Rosas A, Hou D, Castro B, Steffens AM, McCortney K, Walshon JP, Flowers MS, Lin H, Wang H, Zhao J, Sonabend A, Zhang P, Ahmed AU, Brat DJ, Heiland DH, Lee-Chang C, Lesniak MS, Chandel NS, Miska J. Rashidi A, et al. Among authors: chandel ns. Cell Metab. 2024 Jan 2;36(1):62-77.e8. doi: 10.1016/j.cmet.2023.11.013. Epub 2023 Dec 21. Cell Metab. 2024. PMID: 38134929
Octopamine metabolically reprograms astrocytes to confer neuroprotection against α-synuclein.
Shum A, Zaichick S, McElroy GS, D'Alessandro K, Alasady MJ, Novakovic M, Peng W, Grebenik EA, Chung D, Flanagan ME, Smith R, Morales A, Stumpf L, McGrath K, Krainc D, Mendillo ML, Prakriya M, Chandel NS, Caraveo G. Shum A, et al. Among authors: chandel ns. Proc Natl Acad Sci U S A. 2023 Apr 25;120(17):e2217396120. doi: 10.1073/pnas.2217396120. Epub 2023 Apr 17. Proc Natl Acad Sci U S A. 2023. PMID: 37068235 Free PMC article.
312 results