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SARS-CoV-2 infects epithelial cells of the blood-cerebrospinal fluid barrier rather than endothelial cells or pericytes of the blood-brain barrier.
Stüdle C, Nishihara H, Wischnewski S, Kulsvehagen L, Perriot S, Ishikawa H, Schroten H, Frank S, Deigendesch N, Du Pasquier R, Schirmer L, Pröbstel AK, Engelhardt B. Stüdle C, et al. Among authors: engelhardt b. Fluids Barriers CNS. 2023 Oct 24;20(1):76. doi: 10.1186/s12987-023-00479-4. Fluids Barriers CNS. 2023. PMID: 37875964 Free PMC article.
Modeling Brain Vasculature Immune Interactions In Vitro.
Lyck R, Nishihara H, Aydin S, Soldati S, Engelhardt B. Lyck R, et al. Among authors: engelhardt b. Cold Spring Harb Perspect Med. 2023 Sep 1;13(9):a041185. doi: 10.1101/cshperspect.a041185. Cold Spring Harb Perspect Med. 2023. PMID: 36617644 Review.
Correction to: The choroid plexus acts as an immune cell reservoir and brain entry site in experimental autoimmune encephalomyelitis.
Lazarevic I, Soldati S, Mapunda JA, Rudolph H, Rosito M, de Oliveira AC, Enzmann G, Nishihara H, Ishikawa H, Tenenbaum T, Schroten H, Engelhardt B. Lazarevic I, et al. Among authors: engelhardt b. Fluids Barriers CNS. 2023 Jul 14;20(1):55. doi: 10.1186/s12987-023-00457-w. Fluids Barriers CNS. 2023. PMID: 37452369 Free PMC article. No abstract available.
Pericytes Enrich the Basement Membrane and Reduce Neutrophil Transmigration in an In Vitro Model of Peripheral Inflammation at the Blood-Brain Barrier.
McCloskey MC, Ahmad SD, Widom LP, Kasap P, Gastfriend BD, Shusta EV, Palecek SP, Engelhardt B, Gaborski TR, Flax J, Waugh RE, McGrath JL. McCloskey MC, et al. Among authors: engelhardt b. Biomater Res. 2024 Oct 3;28:0081. doi: 10.34133/bmr.0081. eCollection 2024. Biomater Res. 2024. PMID: 39363889 Free PMC article.
Macrophages clear the way for CNS fluid flow.
Proulx ST, Engelhardt B. Proulx ST, et al. Among authors: engelhardt b. Lancet Neurol. 2023 Mar;22(3):194-195. doi: 10.1016/S1474-4422(23)00028-5. Lancet Neurol. 2023. PMID: 36804079 No abstract available.
436 results