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Discovery of INCB159020, an Orally Bioavailable KRAS G12D Inhibitor.
Ye Q, Shvartsbart A, Li Z, Gan P, Policarpo RL, Qi C, Roach JJ, Zhu W, McCammant MS, Hu B, Li G, Yin H, Carlsen P, Hoang G, Zhao L, Susick R, Zhang F, Lai CT, Allali Hassani A, Epling LB, Gallion A, Kurzeja-Lipinski K, Gallagher K, Roman V, Farren MR, Kong W, Deller MC, Zhang G, Covington M, Diamond S, Kim S, Yao W, Sokolsky A, Wang X. Ye Q, et al. Among authors: roach jj. J Med Chem. 2025 Jan 8. doi: 10.1021/acs.jmedchem.4c02662. Online ahead of print. J Med Chem. 2025. PMID: 39772605
Psychology insights on apologizing to patients.
Redelmeier DA, Roach J. Redelmeier DA, et al. Among authors: roach j. J Hosp Med. 2024 Dec 30. doi: 10.1002/jhm.13585. Online ahead of print. J Hosp Med. 2024. PMID: 39739305 No abstract available.
The impact of transplant location on the gut microbiome and resistome in patients undergoing hematopoietic stem cell transplantation at home versus in the hospital.
Andermann TM, Zeng K, Guirales-Medrano S, Groth A, Ramachandran BC, Sun S, Sorgen AA, Hill L, Bush AT, Liu H, Jones C, Roach J, Conlon BP, Rao G, Chao NJ, Fodor AA, Sung AD. Andermann TM, et al. Among authors: roach j. bioRxiv [Preprint]. 2024 Nov 20:2024.11.19.624359. doi: 10.1101/2024.11.19.624359. bioRxiv. 2024. PMID: 39605587 Free PMC article. Preprint.
Generating Biomedical Knowledge Graphs from Knowledge Bases, Registries, and Multiomic Data.
Qin G, Narsinh K, Wei Q, Roach JC, Joshi A, Goetz SL, Moxon ST, Brush MH, Xu C, Yao Y, Glen AK, Morris ED, Ralevski A, Roper R, Belhu B, Zhang Y, Shmulevich I, Hadlock J, Glusman G. Qin G, et al. Among authors: roach jc. bioRxiv [Preprint]. 2024 Nov 15:2024.11.14.623648. doi: 10.1101/2024.11.14.623648. bioRxiv. 2024. PMID: 39605475 Free PMC article. Preprint.
Identification of novel 3D-genome altering and complex structural variants underlying retinitis pigmentosa type 17 through a multistep and high-throughput approach.
de Bruijn SE, Panneman DM, Weisschuh N, Cadena EL, Boonen EGM, Holtes LK, Astuti GDN, Cremers FPM, Leijsten N, Corominas J, Gilissen C, Skowronska A, Woodley J, Beggs AD, Toulis V, Chen D, Cheetham ME, Hardcastle AJ, McLaren TL, Lamey TM, Thompson JA, Chen FK, de Roach JN, Urwin IR, Sullivan LS, Roosing S. de Bruijn SE, et al. Among authors: de roach jn. Front Genet. 2024 Oct 23;15:1469686. doi: 10.3389/fgene.2024.1469686. eCollection 2024. Front Genet. 2024. PMID: 39507620 Free PMC article.
836 results