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Page 1
A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival.
Abassah-Oppong S, Zoia M, Mannion BJ, Rouco R, Tissières V, Spurrell CH, Roland V, Darbellay F, Itum A, Gamart J, Festa-Daroux TA, Sullivan CS, Kosicki M, Rodríguez-Carballo E, Fukuda-Yuzawa Y, Hunter RD, Novak CS, Plajzer-Frick I, Tran S, Akiyama JA, Dickel DE, Lopez-Rios J, Barozzi I, Andrey G, Visel A, Pennacchio LA, Cobb J, Osterwalder M. Abassah-Oppong S, et al. Among authors: spurrell ch. Nat Commun. 2024 Oct 10;15(1):8793. doi: 10.1038/s41467-024-53009-7. Nat Commun. 2024. PMID: 39389973 Free PMC article.
Single-cell analysis of chromatin and expression reveals age- and sex-associated alterations in the human heart.
Read DF, Booth GT, Daza RM, Jackson DL, Gladden RG, Srivatsan SR, Ewing B, Franks JM, Spurrell CH, Gomes AR, O'Day D, Gogate AA, Martin BK, Larson H, Pfleger C, Starita L, Lin Y, Shendure J, Lin S, Trapnell C. Read DF, et al. Among authors: spurrell ch. Commun Biol. 2024 Aug 26;7(1):1052. doi: 10.1038/s42003-024-06582-y. Commun Biol. 2024. PMID: 39187646 Free PMC article.
Dynamic enhancer landscapes in human craniofacial development.
Rajderkar SS, Paraiso K, Amaral ML, Kosicki M, Cook LE, Darbellay F, Spurrell CH, Osterwalder M, Zhu Y, Wu H, Afzal SY, Blow MJ, Kelman G, Barozzi I, Fukuda-Yuzawa Y, Akiyama JA, Afzal V, Tran S, Plajzer-Frick I, Novak CS, Kato M, Hunter RD, von Maydell K, Wang A, Lin L, Preissl S, Lisgo S, Ren B, Dickel DE, Pennacchio LA, Visel A. Rajderkar SS, et al. Among authors: spurrell ch. Nat Commun. 2024 Mar 6;15(1):2030. doi: 10.1038/s41467-024-46396-4. Nat Commun. 2024. PMID: 38448444 Free PMC article.
Context-specific synthetic T cell promoters from assembled transcriptional elements.
Appelbaum J, Wei J, Mukherjee R, Ishida T, Rosser J, Saxby C, Chase J, Carlson M, Sather C, Rahfeldt W, Meechan M, Baldwin M, Flint L, Spurrell C, Gustafson J, Johnson A, Jensen M. Appelbaum J, et al. Among authors: spurrell c. Res Sq [Preprint]. 2023 Oct 17:rs.3.rs-3339290. doi: 10.21203/rs.3.rs-3339290/v1. Res Sq. 2023. PMID: 37886484 Free PMC article. Preprint.
A single-cell multi-omic atlas spanning the adult rhesus macaque brain.
Chiou KL, Huang X, Bohlen MO, Tremblay S, DeCasien AR, O'Day DR, Spurrell CH, Gogate AA, Zintel TM; Cayo Biobank Research Unit; Andrews MG, Martínez MI, Starita LM, Montague MJ, Platt ML, Shendure J, Snyder-Mackler N. Chiou KL, et al. Among authors: spurrell ch. Sci Adv. 2023 Oct 13;9(41):eadh1914. doi: 10.1126/sciadv.adh1914. Epub 2023 Oct 12. Sci Adv. 2023. PMID: 37824616 Free PMC article.
Single-cell census of human tooth development enables generation of human enamel.
Alghadeer A, Hanson-Drury S, Patni AP, Ehnes DD, Zhao YT, Li Z, Phal A, Vincent T, Lim YC, O'Day D, Spurrell CH, Gogate AA, Zhang H, Devi A, Wang Y, Starita L, Doherty D, Glass IA, Shendure J, Freedman BS, Baker D, Regier MC, Mathieu J, Ruohola-Baker H. Alghadeer A, et al. Among authors: spurrell ch. Dev Cell. 2023 Oct 23;58(20):2163-2180.e9. doi: 10.1016/j.devcel.2023.07.013. Epub 2023 Aug 14. Dev Cell. 2023. PMID: 37582367 Free PMC article.
Cell Type- and Tissue-specific Enhancers in Craniofacial Development.
Rajderkar SS, Paraiso K, Amaral ML, Kosicki M, Cook LE, Darbellay F, Spurrell CH, Osterwalder M, Zhu Y, Wu H, Afzal SY, Blow MJ, Kelman G, Barozzi I, Fukuda-Yuzawa Y, Akiyama JA, Afzal V, Tran S, Plajzer-Frick I, Novak CS, Kato M, Hunter RD, von Maydell K, Wang A, Lin L, Preissl S, Lisgo S, Ren B, Dickel DE, Pennacchio LA, Visel A. Rajderkar SS, et al. Among authors: spurrell ch. bioRxiv [Preprint]. 2023 Jun 26:2023.06.26.546603. doi: 10.1101/2023.06.26.546603. bioRxiv. 2023. PMID: 37425964 Free PMC article. Preprint.
Multiregion transcriptomic profiling of the primate brain reveals signatures of aging and the social environment.
Chiou KL, DeCasien AR, Rees KP, Testard C, Spurrell CH, Gogate AA, Pliner HA, Tremblay S, Mercer A, Whalen CJ, Negrón-Del Valle JE, Janiak MC, Bauman Surratt SE, González O, Compo NR, Stock MK, Ruiz-Lambides AV, Martínez MI; Cayo Biobank Research Unit; Wilson MA, Melin AD, Antón SC, Walker CS, Sallet J, Newbern JM, Starita LM, Shendure J, Higham JP, Brent LJN, Montague MJ, Platt ML, Snyder-Mackler N. Chiou KL, et al. Among authors: spurrell ch. Nat Neurosci. 2022 Dec;25(12):1714-1723. doi: 10.1038/s41593-022-01197-0. Epub 2022 Nov 24. Nat Neurosci. 2022. PMID: 36424430 Free PMC article.
Genome-wide fetalization of enhancer architecture in heart disease.
Spurrell CH, Barozzi I, Kosicki M, Mannion BJ, Blow MJ, Fukuda-Yuzawa Y, Slaven N, Afzal SY, Akiyama JA, Afzal V, Tran S, Plajzer-Frick I, Novak CS, Kato M, Lee EA, Garvin TH, Pham QT, Kronshage AN, Lisgo S, Bristow J, Cappola TP, Morley MP, Margulies KB, Pennacchio LA, Dickel DE, Visel A. Spurrell CH, et al. Cell Rep. 2022 Sep 20;40(12):111400. doi: 10.1016/j.celrep.2022.111400. Cell Rep. 2022. PMID: 36130500 Free PMC article.
18 results