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Activation of HIV-1 proviruses increases downstream chromatin accessibility.
Shah R, Gallardo CM, Jung YH, Clock B, Dixon JR, McFadden WM, Majumder K, Pintel DJ, Corces VG, Torbett BE, Tedbury PR, Sarafianos SG. Shah R, et al. Among authors: sarafianos sg. iScience. 2022 Nov 8;25(12):105490. doi: 10.1016/j.isci.2022.105490. eCollection 2022 Dec 22. iScience. 2022. PMID: 36505924 Free PMC article.
Targeting the HIV-1 and HBV Capsids, an EnCore.
McFadden WM, Sarafianos SG. McFadden WM, et al. Among authors: sarafianos sg. Viruses. 2023 Mar 31;15(4):896. doi: 10.3390/v15040896. Viruses. 2023. PMID: 37112877 Free PMC article.
Identification of clickable HIV-1 capsid-targeting probes for viral replication inhibition.
McFadden WM, Casey-Moore MC, Bare GAL, Kirby KA, Wen X, Li G, Wang H, Slack RL, Snyder AA, Lorson ZC, Kaufman IL, Cilento ME, Tedbury PR, Gembicky M, Olson AJ, Torbett BE, Sharpless KB, Sarafianos SG. McFadden WM, et al. Among authors: sarafianos sg. Cell Chem Biol. 2024 Mar 21;31(3):477-486.e7. doi: 10.1016/j.chembiol.2024.02.012. Cell Chem Biol. 2024. PMID: 38518746
Myrtus communis L. Essential Oil Exhibits Antiviral Activity against Coronaviruses.
Li DY, Donadu MG, Shue T, Dangas G, Athanasiadis A, Lan S, Wen X, Battah B, Zanetti S, Mazzarello V, Sarafianos SG, Ferrari M, Michailidis E. Li DY, et al. Among authors: sarafianos sg. Pharmaceuticals (Basel). 2024 Sep 10;17(9):1189. doi: 10.3390/ph17091189. Pharmaceuticals (Basel). 2024. PMID: 39338351 Free PMC article.
Synthesis and biological evaluation of novel peptidomimetic inhibitors of the coronavirus 3C-like protease.
Amblard F, LeCher JC, De R, Zhou S, Liu P, Goh SL, Tao S, Patel D, Downs-Bowen J, Zandi K, Zhang H, Chaudhry G, McBrayer T, Muczynski M, Al-Homoudi A, Engel J, Lan S, Sarafianos SG, Kovari LC, Schinazi RF. Amblard F, et al. Among authors: sarafianos sg. Eur J Med Chem. 2024 Mar 15;268:116263. doi: 10.1016/j.ejmech.2024.116263. Epub 2024 Feb 24. Eur J Med Chem. 2024. PMID: 38432056
The HIV-1 capsid core is an opportunistic nuclear import receptor.
Xue G, Yu HJ, Buffone C, Huang SW, Lee K, Goh SL, Gres AT, Guney MH, Sarafianos SG, Luban J, Diaz-Griffero F, KewalRamani VN. Xue G, et al. Among authors: sarafianos sg. Nat Commun. 2023 Jun 24;14(1):3782. doi: 10.1038/s41467-023-39146-5. Nat Commun. 2023. PMID: 37355754 Free PMC article.
205 results