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415 results

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A human mitofusin 2 mutation can cause mitophagic cardiomyopathy.
Franco A, Li J, Kelly DP, Hershberger RE, Marian AJ, Lewis RM, Song M, Dang X, Schmidt AD, Mathyer ME, Edwards JR, Strong CG, Dorn GW. Franco A, et al. Among authors: kelly dp. Elife. 2023 Nov 1;12:e84235. doi: 10.7554/eLife.84235. Elife. 2023. PMID: 37910431 Free PMC article.
Cardiac NAD+ depletion in mice promotes hypertrophic cardiomyopathy and arrhythmias prior to impaired bioenergetics.
Doan KV, Luongo TS, Ts'olo TT, Lee WD, Frederick DW, Mukherjee S, Adzika GK, Perry CE, Gaspar RB, Walker N, Blair MC, Bye N, Davis JG, Holman CD, Chu Q, Wang L, Rabinowitz JD, Kelly DP, Cappola TP, Margulies KB, Baur JA. Doan KV, et al. Among authors: kelly dp. Nat Cardiovasc Res. 2024 Oct;3(10):1236-1248. doi: 10.1038/s44161-024-00542-9. Epub 2024 Sep 18. Nat Cardiovasc Res. 2024. PMID: 39294272
Targeted Quantitative Plasma Metabolomics Identifies Metabolite Signatures that Distinguish Heart Failure with Reduced and Preserved Ejection Fraction.
Naeem F, Leone TC, Petucci C, Shoffler C, Kodihalli RC, Hidalgo T, Tow-Keogh C, Mancuso J, Tzameli I, Bennett D, Groarke JD, Flach RJR, Rader DJ, Kelly DP. Naeem F, et al. Among authors: kelly dp. medRxiv [Preprint]. 2024 Jul 25:2024.07.24.24310961. doi: 10.1101/2024.07.24.24310961. medRxiv. 2024. PMID: 39108509 Free PMC article. Preprint.
SGLT2 Inhibitors Act Independently of SGLT2 to Confer Benefit for HFrEF in Mice.
Berger JH, Matsuura TR, Bowman CE, Taing R, Patel J, Lai L, Leone TC, Reagan JD, Haldar SM, Arany Z, Kelly DP. Berger JH, et al. Among authors: kelly dp. Circ Res. 2024 Aug 16;135(5):632-634. doi: 10.1161/CIRCRESAHA.124.324823. Epub 2024 Jul 23. Circ Res. 2024. PMID: 39041214 No abstract available.
Two-hit mouse model of heart failure with preserved ejection fraction combining diet-induced obesity and renin-mediated hypertension.
Berger JH, Shi Y, Matsuura TR, Batmanov K, Chen X, Tam K, Marshall M, Kue R, Patel J, Taing R, Callaway R, Griffin J, Kovacs A, Shanthappa DH, Miller R, Zhang BB, Roth Flach RJ, Kelly DP. Berger JH, et al. Among authors: kelly dp. bioRxiv [Preprint]. 2024 Jun 9:2024.06.06.597821. doi: 10.1101/2024.06.06.597821. bioRxiv. 2024. PMID: 38895483 Free PMC article. Preprint.
Sodium-glucose co-transporter 2 Inhibitors Act Independently of SGLT2 to Confer Benefit for Heart Failure with Reduced Ejection Fraction in Mice.
Berger JH, Matsuura TR, Bowman CE, Taing R, Patel J, Lai L, Leone TC, Reagan JD, Haldar SM, Arany Z, Kelly DP. Berger JH, et al. Among authors: kelly dp. bioRxiv [Preprint]. 2024 May 2:2024.04.29.591665. doi: 10.1101/2024.04.29.591665. bioRxiv. 2024. Update in: Circ Res. 2024 Aug 16;135(5):632-634. doi: 10.1161/CIRCRESAHA.124.324823 PMID: 38746425 Free PMC article. Updated. Preprint.
415 results