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Aerosol delivery of SARS-CoV-2 human monoclonal antibodies in macaques limits viral replication and lung pathology.
Streblow DN, Hirsch AJ, Stanton JJ, Lewis AD, Colgin L, Hessell AJ, Kreklywich CN, Smith JL, Sutton WF, Chauvin D, Woo J, Bimber BN, LeBlanc CN, Acharya SN, O'Roak BJ, Sardar H, Sajadi MM, Tehrani ZR, Walter MR, Martinez-Sobrido L, Kobie JJ, Reader RJ, Olstad KJ, Hobbs TR, Saphire EO, Schendel SL, Carnahan RH, Knoch J, Branco LM, Crowe JE Jr, Van Rompay KKA, Lovalenti P, Vu Truong, Forthal DN, Haigwood NL. Streblow DN, et al. Among authors: hessell aj. Nat Commun. 2023 Nov 3;14(1):7062. doi: 10.1038/s41467-023-42440-x. Nat Commun. 2023. PMID: 37923717 Free PMC article.
The MHC class II cofactor HLA-DM interacts with Ig in B cells.
Macmillan H, Strohman MJ, Ayyangar S, Jiang W, Rajasekaran N, Spura A, Hessell AJ, Madec AM, Mellins ED. Macmillan H, et al. Among authors: hessell aj. J Immunol. 2014 Sep 15;193(6):2641-2650. doi: 10.4049/jimmunol.1400075. Epub 2014 Aug 6. J Immunol. 2014. PMID: 25098292 Free PMC article.
Neutralizing epitopes in the membrane-proximal external region of HIV-1 gp41 are influenced by the transmembrane domain and the plasma membrane.
Montero M, Gulzar N, Klaric KA, Donald JE, Lepik C, Wu S, Tsai S, Julien JP, Hessell AJ, Wang S, Lu S, Burton DR, Pai EF, Degrado WF, Scott JK. Montero M, et al. Among authors: hessell aj. J Virol. 2012 Mar;86(6):2930-41. doi: 10.1128/JVI.06349-11. Epub 2012 Jan 11. J Virol. 2012. PMID: 22238313 Free PMC article.
Broadly neutralizing monoclonal antibodies 2F5 and 4E10 directed against the human immunodeficiency virus type 1 gp41 membrane-proximal external region protect against mucosal challenge by simian-human immunodeficiency virus SHIVBa-L.
Hessell AJ, Rakasz EG, Tehrani DM, Huber M, Weisgrau KL, Landucci G, Forthal DN, Koff WC, Poignard P, Watkins DI, Burton DR. Hessell AJ, et al. J Virol. 2010 Feb;84(3):1302-13. doi: 10.1128/JVI.01272-09. Epub 2009 Nov 11. J Virol. 2010. PMID: 19906907 Free PMC article.
74 results