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Wnt activation disturbs cell competition and causes diffuse invasion of transformed cells through NF-κB-MMP21 pathway.
Nakai K, Lin H, Yamano S, Tanaka S, Kitamoto S, Saitoh H, Sakuma K, Kurauchi J, Akter E, Konno M, Ishibashi K, Kamata R, Ohashi A, Koseki J, Takahashi H, Yokoyama H, Shiraki Y, Enomoto A, Abe S, Hayakawa Y, Ushiku T, Mutoh M, Fujita Y, Kon S. Nakai K, et al. Among authors: tanaka s. Nat Commun. 2023 Nov 3;14(1):7048. doi: 10.1038/s41467-023-42774-6. Nat Commun. 2023. PMID: 37923722 Free PMC article.
The CD44/COL17A1 pathway promotes the formation of multilayered, transformed epithelia.
Kozawa K, Sekai M, Ohba K, Ito S, Sako H, Maruyama T, Kakeno M, Shirai T, Kuromiya K, Kamasaki T, Kohashi K, Tanaka S, Ishikawa S, Sato N, Asano S, Suzuki H, Tanimura N, Mukai Y, Gotoh N, Tanino M, Tanaka S, Natsuga K, Soga T, Nakamura T, Yabuta Y, Saitou M, Ito T, Matsuura K, Tsunoda M, Kikumori T, Iida T, Mizutani Y, Miyai Y, Kaibuchi K, Enomoto A, Fujita Y. Kozawa K, et al. Among authors: tanaka s. Curr Biol. 2021 Jul 26;31(14):3086-3097.e7. doi: 10.1016/j.cub.2021.04.078. Epub 2021 Jun 3. Curr Biol. 2021. PMID: 34087104 Free article.
Structural basis for receptor-binding domain mobility of the spike in SARS-CoV-2 BA.2.86 and JN.1.
Yajima H, Anraku Y, Kaku Y, Kimura KT, Plianchaisuk A, Okumura K, Nakada-Nakura Y, Atarashi Y, Hemmi T, Kuroda D, Takahashi Y, Kita S, Sasaki J, Sumita H; Genotype to Phenotype Japan (G2P-Japan) Consortium; Ito J, Maenaka K, Sato K, Hashiguchi T. Yajima H, et al. Nat Commun. 2024 Oct 7;15(1):8574. doi: 10.1038/s41467-024-52808-2. Nat Commun. 2024. PMID: 39375326 Free PMC article.
Analysis of synthetic polymer hydrogel-based generation of leukemia stem cells.
Sawai S, Oda Y, Saito Y, Kuwabara T, Wang L, Tanei ZI, Hirabayashi S, Tsuda M, Gong JP, Manabe A, Tanaka S. Sawai S, et al. Among authors: tanaka s. Biochem Biophys Res Commun. 2025 Jan;744:151149. doi: 10.1016/j.bbrc.2024.151149. Epub 2024 Dec 6. Biochem Biophys Res Commun. 2025. PMID: 39700762
Multiple mutations of SARS-CoV-2 Omicron BA.2 variant orchestrate its virological characteristics.
Kimura I, Yamasoba D, Nasser H, Ito H, Zahradnik J, Wu J, Fujita S, Uriu K, Sasaki J, Tamura T, Suzuki R, Deguchi S, Plianchaisuk A, Yoshimatsu K, Kazuma Y, Mitoma S, Schreiber G, Asakura H, Nagashima M, Sadamasu K, Yoshimura K, Takaori-Kondo A; Genotype to Phenotype Japan (G2P-Japan) Consortium; Ito J, Shirakawa K, Takayama K, Irie T, Hashiguchi T, Nakagawa S, Fukuhara T, Saito A, Ikeda T, Sato K. Kimura I, et al. J Virol. 2023 Oct 31;97(10):e0101123. doi: 10.1128/jvi.01011-23. Epub 2023 Oct 5. J Virol. 2023. PMID: 37796123 Free PMC article.
Akaluc bioluminescence offers superior sensitivity to track in vivo dynamics of SARS-CoV-2 infection.
Tamura T, Ito H, Torii S, Wang L, Suzuki R, Tsujino S, Kamiyama A, Oda Y, Tsuda M, Morioka Y, Suzuki S, Shirakawa K, Sato K, Yoshimatsu K, Matsuura Y, Iwano S, Tanaka S, Fukuhara T. Tamura T, et al. Among authors: tanaka s. iScience. 2024 Mar 29;27(5):109647. doi: 10.1016/j.isci.2024.109647. eCollection 2024 May 17. iScience. 2024. PMID: 38638572 Free PMC article.
Virological characteristics of a SARS-CoV-2-related bat coronavirus, BANAL-20-236.
Fujita S, Plianchaisuk A, Deguchi S, Ito H, Nao N, Wang L, Nasser H, Tamura T, Kimura I, Kashima Y, Suzuki R, Suzuki S, Kida I, Tsuda M, Oda Y, Hashimoto R, Watanabe Y, Uriu K, Yamasoba D, Guo Z, Hinay AA Jr, Kosugi Y, Chen L, Pan L, Kaku Y, Chu H, Donati F, Temmam S, Eloit M, Yamamoto Y, Nagamoto T, Asakura H, Nagashima M, Sadamasu K, Yoshimura K, Suzuki Y; Genotype to Phenotype Japan (G2P-Japan) Consortium; Ito J, Ikeda T, Tanaka S, Matsuno K, Fukuhara T, Takayama K, Sato K. Fujita S, et al. Among authors: tanaka s. EBioMedicine. 2024 Jun;104:105181. doi: 10.1016/j.ebiom.2024.105181. Epub 2024 Jun 4. EBioMedicine. 2024. PMID: 38838469 Free PMC article.
Recently, BANAL-20-236 (B236) was isolated from a rectal swab of Malayan horseshoe bat and was found to lack a furin cleavage site (FCS) in the spike (S) protein. The comparison of its virological characteristics with FCS-deleted SARS-CoV-2 (SC2deltaFCS) has not been condu …
Recently, BANAL-20-236 (B236) was isolated from a rectal swab of Malayan horseshoe bat and was found to lack a furin cleavage site (FCS) in …
13,853 results
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