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Page 1
Preclinical development of a stabilized RH5 virus-like particle vaccine that induces improved antimalarial antibodies.
King LDW, Pulido D, Barrett JR, Davies H, Quinkert D, Lias AM, Silk SE, Pattinson DJ, Diouf A, Williams BG, McHugh K, Rodrigues A, Rigby CA, Strazza V, Suurbaar J, Rees-Spear C, Dabbs RA, Ishizuka AS, Zhou Y, Gupta G, Jin J, Li Y, Carnrot C, Minassian AM, Campeotto I, Fleishman SJ, Noe AR, MacGill RS, King CR, Birkett AJ, Soisson LA, Long CA, Miura K, Ashfield R, Skinner K, Howarth MR, Biswas S, Draper SJ. King LDW, et al. Among authors: rees spear c. Cell Rep Med. 2024 Jul 16;5(7):101654. doi: 10.1016/j.xcrm.2024.101654. Cell Rep Med. 2024. PMID: 39019011 Free PMC article.
TIGIT+Tfh show poor B-helper function and negatively correlate with SARS-CoV-2 antibody titre.
Edner NM, Houghton LP, Ntavli E, Rees-Spear C, Petersone L, Wang C, Fabri A, Elfaki Y, Rueda Gonzalez A, Brown R, Kisand K, Peterson P, McCoy LE, Walker LSK. Edner NM, et al. Among authors: rees spear c. Front Immunol. 2024 May 29;15:1395684. doi: 10.3389/fimmu.2024.1395684. eCollection 2024. Front Immunol. 2024. PMID: 38868776 Free PMC article.
High affinity mAb infusion can enhance maximum affinity maturation during HIV Env immunization.
Thomas P, Rees-Spear C, Griffith S, Muir L, Touizer E, Andrabi R, Priest R, Percival-Alwyn J, Hayward D, Buxton A, Traylen W, Chain B, Wattam T, Nandin IS, McCoy LE. Thomas P, et al. Among authors: rees spear c. iScience. 2024 Mar 11;27(4):109495. doi: 10.1016/j.isci.2024.109495. eCollection 2024 Apr 19. iScience. 2024. PMID: 38550978 Free PMC article.
Preservation of memory B cell homeostasis in an individual producing broadly neutralising antibodies against HIV-1.
Griffith S, Muir L, Suchanek O, Hope J, Pade C, Gibbons JM, Tuong ZK, Fung A, Touizer E, Rees-Spear C, Nans A, Roustan C, Alguel Y, Fink D, Orkin C, Deayton J, Anderson J, Gupta RK, Doores KJ, Cherepanov P, McKnight Á, Clatworthy M, McCoy LE. Griffith S, et al. Among authors: rees spear c. bioRxiv [Preprint]. 2024 Feb 6:2024.02.05.578789. doi: 10.1101/2024.02.05.578789. bioRxiv. 2024. PMID: 38370662 Free PMC article. Preprint.
Natural killer cell responses during SARS-CoV-2 infection and vaccination in people living with HIV-1.
Alrubayyi A, Touizer E, Hameiri-Bowen D, Charlton B, Gea-Mallorquí E, Hussain N, da Costa KAS, Ford R, Rees-Spear C, Fox TA, Williams I, Waters L, Barber TJ, Burns F, Kinloch S, Morris E, Rowland-Jones S, McCoy LE, Peppa D. Alrubayyi A, et al. Among authors: rees spear c. Sci Rep. 2023 Nov 3;13(1):18994. doi: 10.1038/s41598-023-45412-9. Sci Rep. 2023. PMID: 37923825 Free PMC article.
Attenuated humoral responses in HIV after SARS-CoV-2 vaccination linked to B cell defects and altered immune profiles.
Touizer E, Alrubayyi A, Ford R, Hussain N, Gerber PP, Shum HL, Rees-Spear C, Muir L, Gea-Mallorquí E, Kopycinski J, Jankovic D, Jeffery-Smith A, Pinder CL, Fox TA, Williams I, Mullender C, Maan I, Waters L, Johnson M, Madge S, Youle M, Barber TJ, Burns F, Kinloch S, Rowland-Jones S, Gilson R, Matheson NJ, Morris E, Peppa D, McCoy LE. Touizer E, et al. Among authors: rees spear c. iScience. 2023 Jan 20;26(1):105862. doi: 10.1016/j.isci.2022.105862. Epub 2022 Dec 24. iScience. 2023. PMID: 36590902 Free PMC article.
Attenuated humoral responses in HIV infection after SARS-CoV-2 vaccination are linked to global B cell defects and cellular immune profiles.
Touizer E, Alrubbayi A, Ford R, Hussain N, Gerber PP, Shum HL, Rees-Spear C, Muir L, Gea-Mallorquí E, Kopycinski J, Jankovic D, Pinder C, Fox TA, Williams I, Mullender C, Maan I, Waters L, Johnson M, Madge S, Youle M, Barber T, Burns F, Kinloch S, Rowland-Jones S, Gilson R, Matheson NJ, Morris E, Peppa D, McCoy LE. Touizer E, et al. Among authors: rees spear c. bioRxiv [Preprint]. 2022 Nov 11:2022.11.11.516111. doi: 10.1101/2022.11.11.516111. bioRxiv. 2022. Update in: iScience. 2023 Jan 20;26(1):105862. doi: 10.1016/j.isci.2022.105862 PMID: 36380764 Free PMC article. Updated. Preprint.
Author Correction: SARS-CoV-2 evolution during treatment of chronic infection.
Kemp SA, Collier DA, Datir RP, Ferreira IATM, Gayed S, Jahun A, Hosmillo M, Rees-Spear C, Mlcochova P, Lumb IU, Roberts DJ, Chandra A, Temperton N; CITIID-NIHR BioResource COVID-19 Collaboration; COVID-19 Genomics UK (COG-UK) Consortium; Sharrocks K, Blane E, Modis Y, Leigh KE, Briggs JAG, van Gils MJ, Smith KGC, Bradley JR, Smith C, Doffinger R, Ceron-Gutierrez L, Barcenas-Morales G, Pollock DD, Goldstein RA, Smielewska A, Skittrall JP, Gouliouris T, Goodfellow IG, Gkrania-Klotsas E, Illingworth CJR, McCoy LE, Gupta RK. Kemp SA, et al. Among authors: rees spear c. Nature. 2022 Aug;608(7922):E23. doi: 10.1038/s41586-022-05104-2. Nature. 2022. PMID: 35864233 Free PMC article. No abstract available.
Influence of IL-6 levels on patient survival in COVID-19.
Arulkumaran N, Snow TAC, Kulkarni A, Brealey D, Rickman HM, Rees-Spear C, Spyer MJ, Heaney J, Garr E, Williams B, Cherepanov P, Kassiotis G, Lunn MP, Ambler G, Houlihan C, McCoy LE, Nastouli E, Singer M. Arulkumaran N, et al. Among authors: rees spear c. J Crit Care. 2021 Dec;66:123-125. doi: 10.1016/j.jcrc.2021.08.013. Epub 2021 Sep 16. J Crit Care. 2021. PMID: 34537594 Free PMC article. No abstract available.
21 results