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The ubiquitin-like modifier FAT10 is induced in MASLD and impairs the lipid-regulatory activity of PPARα.
Clavreul L, Bernard L, Cotte AK, Hennuyer N, Bourouh C, Devos C, Helleboid A, Haas JT, Verrijken A, Gheeraert C, Derudas B, Guille L, Chevalier J, Eeckhoute J, Vallez E, Dorchies E, Van Gaal L, Lassailly G, Francque S, Staels B, Paumelle R. Clavreul L, et al. Among authors: helleboid a. Metabolism. 2024 Feb;151:155720. doi: 10.1016/j.metabol.2023.155720. Epub 2023 Nov 3. Metabolism. 2024. PMID: 37926201
Nuclear bile acid signaling through the farnesoid X receptor.
Mazuy C, Helleboid A, Staels B, Lefebvre P. Mazuy C, et al. Among authors: helleboid a. Cell Mol Life Sci. 2015 May;72(9):1631-50. doi: 10.1007/s00018-014-1805-y. Epub 2014 Dec 16. Cell Mol Life Sci. 2015. PMID: 25511198 Free PMC article. Review.
Overweight induced by chronic risperidone exposure is correlated with overexpression of the SREBP-1c and FAS genes in mouse liver.
Lauressergues E, Martin F, Helleboid A, Bouchaert E, Cussac D, Bordet R, Hum D, Luc G, Majd Z, Staels B, Duriez P. Lauressergues E, et al. Among authors: helleboid a. Naunyn Schmiedebergs Arch Pharmacol. 2011 Apr;383(4):423-36. doi: 10.1007/s00210-010-0597-3. Epub 2011 Feb 19. Naunyn Schmiedebergs Arch Pharmacol. 2011. PMID: 21336545