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Discontinuation vs. continuation of renin-angiotensin system inhibition before non-cardiac surgery: the SPACE trial.
Ackland GL, Patel A, Abbott TEF, Begum S, Dias P, Crane DR, Somanath S, Middleditch A, Cleland S, Gutierrez Del Arroyo A, Brealey D, Pearse RM; Stopping Perioperative ACE-inhibitors or angiotensin-II receptor blockers (SPACE) trial investigators. Ackland GL, et al. Among authors: begum s. Eur Heart J. 2024 Apr 1;45(13):1146-1155. doi: 10.1093/eurheartj/ehad716. Eur Heart J. 2024. PMID: 37935833 Free PMC article. Clinical Trial.
Preoperative N-terminal pro-B-type natriuretic peptide and myocardial injury after stopping or continuing renin-angiotensin system inhibitors in noncardiac surgery: a prespecified analysis of a phase 2 randomised controlled multicentre trial.
Gutierrez Del Arroyo A, Patel A, Abbott TEF, Begum S, Dias P, Somanath S, Middleditch A, Cleland S, Brealey D, Pearse RM, Ackland GL; SPACE trial investigators. Gutierrez Del Arroyo A, et al. Among authors: begum s. Br J Anaesth. 2024 May;132(5):857-866. doi: 10.1016/j.bja.2024.01.010. Epub 2024 Feb 9. Br J Anaesth. 2024. PMID: 38341283 Free PMC article. Clinical Trial.
Preoperative activation of the renin-angiotensin system and myocardial injury in noncardiac surgery: exploratory mechanistic analysis of the SPACE randomised controlled trial.
Gutierrez Del Arroyo A, Abbott TEF, Patel A, Begum S, Dias P, Brealey D, Pearse RM, Kapil V, Ackland GL; SPACE trial investigators. Gutierrez Del Arroyo A, et al. Among authors: begum s. Br J Anaesth. 2024 Dec 20:S0007-0912(24)00703-7. doi: 10.1016/j.bja.2024.10.040. Online ahead of print. Br J Anaesth. 2024. PMID: 39709293 Free article.
1,047 results