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Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis.
Jin Y, Ding Y, Richards M, Kaakinen M, Giese W, Baumann E, Szymborska A, Rosa A, Nordling S, Schimmel L, Akmeriç EB, Pena A, Nwadozi E, Jamalpour M, Holstein K, Sáinz-Jaspeado M, Bernabeu MO, Welsh M, Gordon E, Franco CA, Vestweber D, Eklund L, Gerhardt H, Claesson-Welsh L. Jin Y, et al. Among authors: vestweber d. Nat Cardiovasc Res. 2022 Dec 7;1(12):1156-1173. doi: 10.1038/s44161-022-00172-z. Nat Cardiovasc Res. 2022. PMID: 37936984 Free PMC article.
Sinusoidal and lymphatic vessel growth is controlled by reciprocal VEGF-C-CDH5 inhibition.
Sung DC, Chen M, Dominguez MH, Mahadevan A, Chen X, Yang J, Gao S, Ren AA, Tang AT, Mericko P, Patton R, Lee M, Jannaway M, Nottebaum A, Vestweber D, Scallan JP, Kahn ML. Sung DC, et al. Among authors: vestweber d. Nat Cardiovasc Res. 2022 Nov;1(11):1006-1021. doi: 10.1038/s44161-022-00147-0. Epub 2022 Nov 11. Nat Cardiovasc Res. 2022. PMID: 36910472 Free PMC article.
Report from the 2023 workshop on endothelial permeability, edema and inflammation.
Vestweber D, Claesson-Welsh L, McDonald DM, Williams T, Schwartz MA, Scallan J, Gavins FNE, van Buul J, Gamble J, Vadas M, Annex BH, Messe SR, Perretti M, André H, Ferrara N, Hla T, Nourshargh S, Simons M. Vestweber D, et al. Nat Cardiovasc Res. 2023 Dec;2(12):1120-1124. doi: 10.1038/s44161-023-00385-w. Nat Cardiovasc Res. 2023. PMID: 39196154 No abstract available.
Endothelial cell sphingosine 1-phosphate receptor 1 restrains VE-cadherin cleavage and attenuates experimental inflammatory arthritis.
Burg N, Malpass R, Alex L, Tran M, Englebrecht E, Kuo A, Pannelini T, Minett M, Athukorala K, Worgall T, Faust HJ, Goodman S, Mehta B, Brenner M, Vestweber D, Wei K, Blobel C, Hla T, Salmon JE. Burg N, et al. Among authors: vestweber d. JCI Insight. 2024 Jun 10;9(11):e171467. doi: 10.1172/jci.insight.171467. JCI Insight. 2024. PMID: 38855867 Free PMC article.
An agonistic anti-Tie2 antibody suppresses the normal-to-tumor vascular transition in the glioblastoma invasion zone.
Lee E, Lee EA, Kong E, Chon H, Llaiqui-Condori M, Park CH, Park BY, Kang NR, Yoo JS, Lee HS, Kim HS, Park SH, Choi SW, Vestweber D, Lee JH, Kim P, Lee WS, Kim I. Lee E, et al. Among authors: vestweber d. Exp Mol Med. 2023 Feb;55(2):470-484. doi: 10.1038/s12276-023-00939-9. Epub 2023 Feb 24. Exp Mol Med. 2023. PMID: 36828931 Free PMC article.
Conditions that promote transcellular neutrophil migration in vivo.
Xia M, Stegmeyer RI, Shirakura K, Butz S, Thiriot A, von Andrian UH, Vestweber D. Xia M, et al. Among authors: vestweber d. Sci Rep. 2024 Jun 24;14(1):14471. doi: 10.1038/s41598-024-65173-3. Sci Rep. 2024. PMID: 38914623 Free PMC article.
302 results