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Manipulating the 3D organization of the largest synthetic yeast chromosome.
Zhang W, Lazar-Stefanita L, Yamashita H, Shen MJ, Mitchell LA, Kurasawa H, Lobzaev E, Fanfani V, Haase MAB, Sun X, Jiang Q, Goldberg GW, Ichikawa DM, Lauer SL, McCulloch LH, Easo N, Lin SJ, Camellato BR, Zhu Y, Cai J, Xu Z, Zhao Y, Sacasa M; Build-A-Genome Class; Noyes MB, Bader JS, Deutsch S, Stracquadanio G, Aizawa Y, Dai J, Boeke JD. Zhang W, et al. Among authors: noyes mb. Mol Cell. 2023 Dec 7;83(23):4424-4437.e5. doi: 10.1016/j.molcel.2023.10.015. Epub 2023 Nov 8. Mol Cell. 2023. PMID: 37944526 Free article.
Oncogenic inspiration for programmable activators.
Ichikawa D, Noyes M. Ichikawa D, et al. Cell Genom. 2022 Apr 13;2(4):100122. doi: 10.1016/j.xgen.2022.100122. eCollection 2022 Apr 13. Cell Genom. 2022. PMID: 36776529 Free PMC article.
The State of Systems Genetics in 2017.
Baliga NS, Björkegren JL, Boeke JD, Boutros M, Crawford NP, Dudley AM, Farber CR, Jones A, Levey AI, Lusis AJ, Mak HC, Nadeau JH, Noyes MB, Petretto E, Seyfried NT, Steinmetz LM, Vonesch SC. Baliga NS, et al. Among authors: noyes mb. Cell Syst. 2017 Jan 25;4(1):7-15. doi: 10.1016/j.cels.2017.01.005. Cell Syst. 2017. PMID: 28125793 Free article.
Engineered transcription-associated Cas9 targeting in eukaryotic cells.
Goldberg GW, Kogenaru M, Keegan S, Haase MAB, Kagermazova L, Arias MA, Onyebeke K, Adams S, Beyer DK, Fenyö D, Noyes MB, Boeke JD. Goldberg GW, et al. Among authors: noyes mb. Nat Commun. 2024 Nov 27;15(1):10287. doi: 10.1038/s41467-024-54629-9. Nat Commun. 2024. PMID: 39604381 Free PMC article.
Engineered transcription-associated Cas9 targeting in eukaryotic cells.
Goldberg GW, Kogenaru M, Keegan S, Haase MAB, Kagermazova L, Arias MA, Onyebeke K, Adams S, Beyer DK, Fenyö D, Noyes MB, Boeke JD. Goldberg GW, et al. Among authors: noyes mb. bioRxiv [Preprint]. 2024 Aug 18:2023.09.18.558319. doi: 10.1101/2023.09.18.558319. bioRxiv. 2024. Update in: Nat Commun. 2024 Nov 27;15(1):10287. doi: 10.1038/s41467-024-54629-9 PMID: 37781609 Free PMC article. Updated. Preprint.
A universal deep-learning model for zinc finger design enables transcription factor reprogramming.
Ichikawa DM, Abdin O, Alerasool N, Kogenaru M, Mueller AL, Wen H, Giganti DO, Goldberg GW, Adams S, Spencer JM, Razavi R, Nim S, Zheng H, Gionco C, Clark FT, Strokach A, Hughes TR, Lionnet T, Taipale M, Kim PM, Noyes MB. Ichikawa DM, et al. Among authors: noyes mb. Nat Biotechnol. 2023 Aug;41(8):1117-1129. doi: 10.1038/s41587-022-01624-4. Epub 2023 Jan 26. Nat Biotechnol. 2023. PMID: 36702896 Free PMC article.
34 results