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Structural divergence creates new functional features in alphavirus genomes.
Kutchko KM, Madden EA, Morrison C, Plante KS, Sanders W, Vincent HA, Cruz Cisneros MC, Long KM, Moorman NJ, Heise MT, Laederach A. Kutchko KM, et al. Among authors: heise mt. Nucleic Acids Res. 2018 Apr 20;46(7):3657-3670. doi: 10.1093/nar/gky012. Nucleic Acids Res. 2018. PMID: 29361131 Free PMC article.
Host kinase CSNK2 is a target for inhibition of pathogenic β-coronaviruses including SARS-CoV-2.
Yang X, Dickmander RJ, Bayati A, Taft-Benz SA, Smith JL, Wells CI, Madden EA, Brown JW, Lenarcic EM, Yount BL Jr, Chang E, Axtman AD, Baric RS, Heise MT, McPherson PS, Moorman NJ, Willson TM. Yang X, et al. Among authors: heise mt. bioRxiv [Preprint]. 2022 Jan 26:2022.01.03.474779. doi: 10.1101/2022.01.03.474779. bioRxiv. 2022. Update in: ACS Chem Biol. 2022 Jul 15;17(7):1937-1950. doi: 10.1021/acschembio.2c00378 PMID: 35018375 Free PMC article. Updated. Preprint.
Host Kinase CSNK2 is a Target for Inhibition of Pathogenic SARS-like β-Coronaviruses.
Yang X, Dickmander RJ, Bayati A, Taft-Benz SA, Smith JL, Wells CI, Madden EA, Brown JW, Lenarcic EM, Yount BL Jr, Chang E, Axtman AD, Baric RS, Heise MT, McPherson PS, Moorman NJ, Willson TM. Yang X, et al. Among authors: heise mt. ACS Chem Biol. 2022 Jul 15;17(7):1937-1950. doi: 10.1021/acschembio.2c00378. Epub 2022 Jun 19. ACS Chem Biol. 2022. PMID: 35723434 Free PMC article.
A Multitrait Locus Regulates Sarbecovirus Pathogenesis.
Schäfer A, Leist SR, Gralinski LE, Martinez DR, Winkler ES, Okuda K, Hawkins PE, Gully KL, Graham RL, Scobey DT, Bell TA, Hock P, Shaw GD, Loome JF, Madden EA, Anderson E, Baxter VK, Taft-Benz SA, Zweigart MR, May SR, Dong S, Clark M, Miller DR, Lynch RM, Heise MT, Tisch R, Boucher RC, Pardo Manuel de Villena F, Montgomery SA, Diamond MS, Ferris MT, Baric RS. Schäfer A, et al. Among authors: heise mt. mBio. 2022 Aug 30;13(4):e0145422. doi: 10.1128/mbio.01454-22. Epub 2022 Jul 12. mBio. 2022. PMID: 35862771 Free PMC article.
Forward genetic screen of homeostatic antibody levels in the Collaborative Cross identifies MBD1 as a novel regulator of B cell homeostasis.
Hampton BK, Plante KS, Whitmore AC, Linnertz CL, Madden EA, Noll KE, Boyson SP, Parotti B, Xenakis JG, Bell TA, Hock P, Shaw GD, de Villena FP, Ferris MT, Heise MT. Hampton BK, et al. Among authors: heise mt. PLoS Genet. 2022 Dec 27;18(12):e1010548. doi: 10.1371/journal.pgen.1010548. eCollection 2022 Dec. PLoS Genet. 2022. PMID: 36574452 Free PMC article.
165 results