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Distinct disease mutations in DNMT3A result in a spectrum of behavioral, epigenetic, and transcriptional deficits.
Beard DC, Zhang X, Wu DY, Martin JR, Erickson A, Boua JV, Hamagami N, Swift RG, McCullough KB, Ge X, Bell-Hensley A, Zheng H, Palmer CW, Fuhler NA, Lawrence AB, Hill CA, Papouin T, Noguchi KK, McAlinden A, Garbow JR, Dougherty JD, Maloney SE, Gabel HW. Beard DC, et al. Among authors: mccullough kb. Cell Rep. 2023 Nov 28;42(11):113411. doi: 10.1016/j.celrep.2023.113411. Epub 2023 Nov 11. Cell Rep. 2023. PMID: 37952155 Free PMC article.
A viral toolkit for recording transcription factor-DNA interactions in live mouse tissues.
Cammack AJ, Moudgil A, Chen J, Vasek MJ, Shabsovich M, McCullough K, Yen A, Lagunas T, Maloney SE, He J, Chen X, Hooda M, Wilkinson MN, Miller TM, Mitra RD, Dougherty JD. Cammack AJ, et al. Proc Natl Acad Sci U S A. 2020 May 5;117(18):10003-10014. doi: 10.1073/pnas.1918241117. Epub 2020 Apr 16. Proc Natl Acad Sci U S A. 2020. PMID: 32300008 Free PMC article.
The trajectory of gait development in mice.
Akula SK, McCullough KB, Weichselbaum C, Dougherty JD, Maloney SE. Akula SK, et al. Among authors: mccullough kb. Brain Behav. 2020 Jun;10(6):e01636. doi: 10.1002/brb3.1636. Epub 2020 Apr 24. Brain Behav. 2020. PMID: 32333523 Free PMC article.
A MYT1L syndrome mouse model recapitulates patient phenotypes and reveals altered brain development due to disrupted neuronal maturation.
Chen J, Lambo ME, Ge X, Dearborn JT, Liu Y, McCullough KB, Swift RG, Tabachnick DR, Tian L, Noguchi K, Garbow JR, Constantino JN, Gabel HW, Hengen KB, Maloney SE, Dougherty JD. Chen J, et al. Among authors: mccullough kb. Neuron. 2021 Dec 1;109(23):3775-3792.e14. doi: 10.1016/j.neuron.2021.09.009. Epub 2021 Oct 5. Neuron. 2021. PMID: 34614421 Free PMC article.
Extensive characterization of a Williams Syndrome murine model shows Gtf2ird1 -mediated rescue of select sensorimotor tasks, but no effect on enhanced social behavior.
Nygaard KR, Maloney SE, Swift RG, McCullough KB, Wagner RE, Fass SB, Garbett K, Mirnics K, Veenstra-VanderWeele J, Dougherty JD. Nygaard KR, et al. Among authors: mccullough kb. bioRxiv [Preprint]. 2023 Jan 18:2023.01.18.523029. doi: 10.1101/2023.01.18.523029. bioRxiv. 2023. Update in: Genes Brain Behav. 2023 Aug;22(4):e12853. doi: 10.1111/gbb.12853 PMID: 36711815 Free PMC article. Updated. Preprint.
46 results