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Page 1
YAP-Driven Malignant Reprogramming of Epithelial Stem Cells at Single Cell Resolution.
Gutkind JS, Faraji F, Ramirez S, Clubb L, Sato K, Quiroz PA, Galloway W, Mikulski Z, Hoang T, Medetgul-Ernar K, Marangoni P, Jones K, Officer A, Molinolo A, Kim K, Sakaguchi K, Califano J, Smith Q, Klein O, Tamayo P. Gutkind JS, et al. Among authors: clubb l. Res Sq [Preprint]. 2023 Oct 27:rs.3.rs-3426301. doi: 10.21203/rs.3.rs-3426301/v1. Res Sq. 2023. PMID: 37961717 Free PMC article. Preprint.
Lymphatic-preserving treatment sequencing with immune checkpoint inhibition unleashes cDC1-dependent antitumor immunity in HNSCC.
Saddawi-Konefka R, O'Farrell A, Faraji F, Clubb L, Allevato MM, Jensen SM, Yung BS, Wang Z, Wu VH, Anang NA, Msari RA, Schokrpur S, Pietryga IF, Molinolo AA, Mesirov JP, Simon AB, Fox BA, Bui JD, Sharabi A, Cohen EEW, Califano JA, Gutkind JS. Saddawi-Konefka R, et al. Among authors: clubb l. Nat Commun. 2022 Jul 25;13(1):4298. doi: 10.1038/s41467-022-31941-w. Nat Commun. 2022. PMID: 35879302 Free PMC article.
The GPCR-Gαs-PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure.
Wu VH, Yung BS, Faraji F, Saddawi-Konefka R, Wang Z, Wenzel AT, Song MJ, Pagadala MS, Clubb LM, Chiou J, Sinha S, Matic M, Raimondi F, Hoang TS, Berdeaux R, Vignali DAA, Iglesias-Bartolome R, Carter H, Ruppin E, Mesirov JP, Gutkind JS. Wu VH, et al. Among authors: clubb lm. Nat Immunol. 2023 Aug;24(8):1318-1330. doi: 10.1038/s41590-023-01529-7. Epub 2023 Jun 12. Nat Immunol. 2023. PMID: 37308665 Free PMC article.
The landscape of cancer rewired GPCR signaling axes.
Arora C, Matic M, DiChiaro P, Rosa NO, Carli F, Clubb L, Fard LAN, Kargas G, Diaferia G, Vukotic R, Licata L, Wu G, Natoli G, Gutkind JS, Raimondi F. Arora C, et al. Among authors: clubb l. bioRxiv [Preprint]. 2023 Oct 11:2023.03.13.532291. doi: 10.1101/2023.03.13.532291. bioRxiv. 2023. Update in: Cell Genom. 2024 May 8;4(5):100557. doi: 10.1016/j.xgen.2024.100557 PMID: 37398064 Free PMC article. Updated. Preprint.
Gαs is dispensable for β-arrestin coupling but dictates GRK selectivity and is predominant for gene expression regulation by β2-adrenergic receptor.
Burghi V, Paradis JS, Officer A, Adame-Garcia SR, Wu X, Matthees ESF, Barsi-Rhyne B, Ramms DJ, Clubb L, Acosta M, Tamayo P, Bouvier M, Inoue A, von Zastrow M, Hoffmann C, Gutkind JS. Burghi V, et al. Among authors: clubb l. J Biol Chem. 2023 Nov;299(11):105293. doi: 10.1016/j.jbc.2023.105293. Epub 2023 Sep 27. J Biol Chem. 2023. PMID: 37774973 Free PMC article.
The landscape of cancer-rewired GPCR signaling axes.
Arora C, Matic M, Bisceglia L, Di Chiaro P, De Oliveira Rosa N, Carli F, Clubb L, Nemati Fard LA, Kargas G, Diaferia GR, Vukotic R, Licata L, Wu G, Natoli G, Gutkind JS, Raimondi F. Arora C, et al. Among authors: clubb l. Cell Genom. 2024 May 8;4(5):100557. doi: 10.1016/j.xgen.2024.100557. Cell Genom. 2024. PMID: 38723607 Free PMC article.
The management of acute complete ruptures of the ulnar collateral ligament of the thumb.
Mikhail M, Riley N, Rodrigues J, Carr E, Horton R, Beale N, Beard DJ, Dean BJF; UCL TEAR Collaborative; Clubb L, Johnstone A, Lawrie D, Imam M, Joyce S, Ankarth S, Capp R, Dayananda K, Gape N, Trickett R, Bremner-Smith A, Chan C, Eckersley R, Horwitz M, Jatan A, Lumsdaine W, McArthur G, Mee S, Banks L, Dean S, Dehbozorgi S, Green K, Meh S, Fawkes F, Rooker J, Bell H, Vaghela K, Fournier K, Kennedy D, Li L, Srinivasan S, Gamble D, Gerakopoulos E, Groves J, Jackson T, Karuppaiah K, Maltby A, Nair A, Reichert I, Bains R, Mariathas C, Reilly F, Sharpe L, Wildin C, Feeney M, Kulkarni A, Sharma V, Flaherty S, Gough A, Hamlin K, King L, Law C, Johnson S, Svee C, Khan Y, Rodgers S, Storey P, Dean B, Sander-Danby L, Shields K, Torkington M, Blackshaw R, Chaudhry T, Jordan L, Wu F, Clarke D, Robinson E, Thumbadoo R, Parkinson M, Sharpe K, Allen M, Poulter R, Currie J, Stone O, Cliff N, Duckworth A, Cowey A, Crossfield J, Giddins G, Heath R, Langdon I, Mgbemena L, Mills R, Pickering G, Sheriff M, McDonough A, Naqui Z, Lyons N, Reay E, Taylor T, Bates M, Eastwood G, McLoughlin-Symon I, Ramesh A, Chan J, Govilkar P, Shirley R, Upson C, Sajid S, Carr E, Langley C, Higgins J, Armstrong A,… See abstract for full author list ➔ Mikhail M, et al. Among authors: clubb l. Bone Jt Open. 2024 Aug 22;5(8):708-714. doi: 10.1302/2633-1462.58.BJO-2024-0062.R1. Bone Jt Open. 2024. PMID: 39168472 Free PMC article.
YAP-Driven Oral Epithelial Stem Cell Malignant Reprogramming at Single Cell Resolution.
Faraji F, Ramirez SI, Clubb L, Sato K, Burghi V, Hoang TS, Officer A, Anguiano Quiroz PY, Galloway WM, Mikulski Z, Medetgul-Ernar K, Marangoni P, Jones KB, Molinolo AA, Kim K, Sakaguchi K, Califano JA, Smith Q, Goren A, Klein OD, Tamayo P, Gutkind JS. Faraji F, et al. Among authors: clubb l. bioRxiv [Preprint]. 2024 Oct 21:2023.07.24.550427. doi: 10.1101/2023.07.24.550427. bioRxiv. 2024. PMID: 37546810 Free PMC article. Preprint.
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