Gilbreth RN - Search Results

1

Antitumor activity of AZD0754, a dnTGFβRII-armored, STEAP2-targeted CAR-T cell therapy, in prostate cancer.

Zanvit P, van Dyk D, Fazenbaker C, McGlinchey K, Luo W, Pezold JM, Meekin J, Chang CY, Carrasco RA, Breen S, Cheung CS, Endlich-Frazier A, Clark B, Chu NJ, Vantellini A, Martin PL, Hoover CE, Riley K, Sweet SM, Chain D, Kim YJ, Tu E, Harder N, Phipps S, Damschroder M, Gilbreth RN, Cobbold M, Moody G, Bosco EE. Zanvit P, et al. Among authors: gilbreth rn. J Clin Invest. 2023 Nov 15;133(22):e169655. doi: 10.1172/JCI169655. J Clin Invest. 2023. PMID: 37966111 Free PMC article.

2

Redirecting the specificity of tripartite motif containing-21 scaffolds using a novel discovery and design approach.

VanDyke D, Xu L, Sargunas PR, Gilbreth RN, Baca M, Gao C, Hunt J, Spangler JB. VanDyke D, et al. Among authors: gilbreth rn. J Biol Chem. 2023 Dec;299(12):105381. doi: 10.1016/j.jbc.2023.105381. Epub 2023 Oct 21. J Biol Chem. 2023. PMID: 37866632 Free PMC article.

3

Crystal structure of the human 4-1BB/4-1BBL complex.

Gilbreth RN, Oganesyan VY, Amdouni H, Novarra S, Grinberg L, Barnes A, Baca M. Gilbreth RN, et al. J Biol Chem. 2018 Jun 22;293(25):9880-9891. doi: 10.1074/jbc.RA118.002803. Epub 2018 May 2. J Biol Chem. 2018. PMID: 29720399 Free PMC article.

4

Lipid- and polyion complex-based micelles as agonist platforms for TNFR superfamily receptors.

Gilbreth RN, Novarra S, Wetzel L, Florinas S, Cabral H, Kataoka K, Rios-Doria J, Christie RJ, Baca M. Gilbreth RN, et al. J Control Release. 2016 Jul 28;234:104-14. doi: 10.1016/j.jconrel.2016.05.041. Epub 2016 May 17. J Control Release. 2016. PMID: 27212104

5

Stabilization of the third fibronectin type III domain of human tenascin-C through minimal mutation and rational design.

Gilbreth RN, Chacko BM, Grinberg L, Swers JS, Baca M. Gilbreth RN, et al. Protein Eng Des Sel. 2014 Oct;27(10):411-8. doi: 10.1093/protein/gzu024. Epub 2014 Jul 4. Protein Eng Des Sel. 2014. PMID: 24996411

6

Structural insights for engineering binding proteins based on non-antibody scaffolds.

Gilbreth RN, Koide S. Gilbreth RN, et al. Curr Opin Struct Biol. 2012 Aug;22(4):413-20. doi: 10.1016/j.sbi.2012.06.001. Epub 2012 Jun 27. Curr Opin Struct Biol. 2012. PMID: 22749196 Free PMC article. Review.

7

Teaching an old scaffold new tricks: monobodies constructed using alternative surfaces of the FN3 scaffold.

Koide A, Wojcik J, Gilbreth RN, Hoey RJ, Koide S. Koide A, et al. Among authors: gilbreth rn. J Mol Biol. 2012 Jan 13;415(2):393-405. doi: 10.1016/j.jmb.2011.12.019. Epub 2011 Dec 16. J Mol Biol. 2012. PMID: 22198408 Free PMC article.

8

Isoform-specific monobody inhibitors of small ubiquitin-related modifiers engineered using structure-guided library design.

Gilbreth RN, Truong K, Madu I, Koide A, Wojcik JB, Li NS, Piccirilli JA, Chen Y, Koide S. Gilbreth RN, et al. Proc Natl Acad Sci U S A. 2011 May 10;108(19):7751-6. doi: 10.1073/pnas.1102294108. Epub 2011 Apr 25. Proc Natl Acad Sci U S A. 2011. PMID: 21518904 Free PMC article.

9

Accelerating phage-display library selection by reversible and site-specific biotinylation.

Koide A, Wojcik J, Gilbreth RN, Reichel A, Piehler J, Koide S. Koide A, et al. Among authors: gilbreth rn. Protein Eng Des Sel. 2009 Nov;22(11):685-90. doi: 10.1093/protein/gzp053. Epub 2009 Sep 8. Protein Eng Des Sel. 2009. PMID: 19737805 Free PMC article.

10

A dominant conformational role for amino acid diversity in minimalist protein-protein interfaces.

Gilbreth RN, Esaki K, Koide A, Sidhu SS, Koide S. Gilbreth RN, et al. J Mol Biol. 2008 Aug 29;381(2):407-18. doi: 10.1016/j.jmb.2008.06.014. Epub 2008 Jun 12. J Mol Biol. 2008. PMID: 18602117 Free PMC article.

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