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Page 1
Mapping disease regulatory circuits at cell-type resolution from single-cell multiomics data.
Chen X, Wang Y, Cappuccio A, Cheng WS, Zamojski FR, Nair VD, Miller CM, Rubenstein AB, Nudelman G, Tadych A, Theesfeld CL, Vornholt A, George MC, Ruffin F, Dagher M, Chawla DG, Soares-Schanoski A, Spurbeck RR, Ndhlovu LC, Sebra R, Kleinstein SH, Letizia AG, Ramos I, Fowler VG Jr, Woods CW, Zaslavsky E, Troyanskaya OG, Sealfon SC. Chen X, et al. Among authors: chawla dg. Nat Comput Sci. 2023 Jul;3(7):644-657. doi: 10.1038/s43588-023-00476-5. Epub 2023 Jul 25. Nat Comput Sci. 2023. PMID: 37974651 Free PMC article.
Pan-vaccine analysis reveals innate immune endotypes predictive of antibody responses to vaccination.
Fourati S, Tomalin LE, Mulè MP, Chawla DG, Gerritsen B, Rychkov D, Henrich E, Miller HER, Hagan T, Diray-Arce J, Dunn P; Human Immunology Project Consortium (HIPC); Levy O, Gottardo R, Sarwal MM, Tsang JS, Suárez-Fariñas M, Pulendran B, Kleinstein SH, Sékaly RP. Fourati S, et al. Among authors: chawla dg. Nat Immunol. 2022 Dec;23(12):1777-1787. doi: 10.1038/s41590-022-01329-5. Epub 2022 Oct 31. Nat Immunol. 2022. PMID: 36316476 Free PMC article.
A curated collection of human vaccination response signatures.
Smith KC, Chawla DG, Dhillon BK, Ji Z, Vita R, van der Leest EC, Weng JYJ, Tang E, Abid A; Human Immunology Project Consortium (HIPC); Peters B, Hancock REW, Floratos A, Kleinstein SH. Smith KC, et al. Among authors: chawla dg. Sci Data. 2022 Nov 8;9(1):678. doi: 10.1038/s41597-022-01558-1. Sci Data. 2022. PMID: 36347894 Free PMC article.
Multi-objective optimization identifies a specific and interpretable COVID-19 host response signature.
Cappuccio A, Chawla DG, Chen X, Rubenstein AB, Cheng WS, Mao W, Burke TW, Tsalik EL, Petzold E, Henao R, McClain MT, Woods CW, Chikina M, Troyanskaya OG, Sealfon SC, Kleinstein SH, Zaslavsky E. Cappuccio A, et al. Among authors: chawla dg. Cell Syst. 2022 Dec 21;13(12):989-1001.e8. doi: 10.1016/j.cels.2022.11.008. Cell Syst. 2022. PMID: 36549275 Free article.
Multiomics integration of 22 immune-mediated monogenic diseases reveals an emergent axis of human immune health.
Sparks R, Rachmaninoff N, Hirsch DC, Bansal N, Lau WW, Martins AJ, Chen J, Liu CC, Cheung F, Failla LE, Biancotto A, Fantoni G, Sellers BA, Chawla DG, Howe KN, Mostaghimi D, Farmer R, Kotliarov Y, Calvo KR, Palmer C, Daub J, Foruraghi L, Kreuzburg S, Treat J, Urban AK, Jones A, Romeo T, Deuitch NT, Moura NS, Weinstein B, Moir S, Ferrucci L, Barron KS, Aksentijevich I, Kleinstein SH, Townsley DM, Young NS, Frischmeyer-Guerrerio PA, Uzel G, Pinto-Patarroyo GP, Cudrici CD, Hoffmann P, Stone DL, Ombrello AK, Freeman AF, Zerbe CS, Kastner DL, Holland SM, Tsang JS. Sparks R, et al. Among authors: chawla dg. Res Sq [Preprint]. 2023 Mar 20:rs.3.rs-2070975. doi: 10.21203/rs.3.rs-2070975/v1. Res Sq. 2023. Update in: Nat Med. 2024 Sep;30(9):2461-2472. doi: 10.1038/s41591-024-03092-6 PMID: 36993430 Free PMC article. Updated. Preprint.
Author Correction: Mapping disease regulatory circuits at cell-type resolution from single-cell multiomics data.
Chen X, Wang Y, Cappuccio A, Cheng WS, Zamojski FR, Nair VD, Miller CM, Rubenstein AB, Nudelman G, Tadych A, Theesfeld CL, Vornholt A, George MC, Ruffin F, Dagher M, Chawla DG, Soares-Schanoski A, Spurbeck RR, Ndhlovu LC, Sebra R, Kleinstein SH, Letizia AG, Ramos I, Fowler VG Jr, Woods CW, Zaslavsky E, Troyanskaya OG, Sealfon SC. Chen X, et al. Among authors: chawla dg. Nat Comput Sci. 2023 Sep;3(9):805. doi: 10.1038/s43588-023-00523-1. Nat Comput Sci. 2023. PMID: 38177788 Free PMC article. No abstract available.
A unified metric of human immune health.
Sparks R, Rachmaninoff N, Lau WW, Hirsch DC, Bansal N, Martins AJ, Chen J, Liu CC, Cheung F, Failla LE, Biancotto A, Fantoni G, Sellers BA, Chawla DG, Howe KN, Mostaghimi D, Farmer R, Kotliarov Y, Calvo KR, Palmer C, Daub J, Foruraghi L, Kreuzburg S, Treat JD, Urban AK, Jones A, Romeo T, Deuitch NT, Moura NS, Weinstein B, Moir S, Ferrucci L, Barron KS, Aksentijevich I, Kleinstein SH, Townsley DM, Young NS, Frischmeyer-Guerrerio PA, Uzel G, Pinto-Patarroyo GP, Cudrici CD, Hoffmann P, Stone DL, Ombrello AK, Freeman AF, Zerbe CS, Kastner DL, Holland SM, Tsang JS. Sparks R, et al. Among authors: chawla dg. Nat Med. 2024 Sep;30(9):2461-2472. doi: 10.1038/s41591-024-03092-6. Epub 2024 Jul 3. Nat Med. 2024. PMID: 38961223
14 results