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Page 1
Molecular and functional profiling of chemotolerant cells unveils nucleoside metabolism-dependent vulnerabilities in medulloblastoma.
Mariotto E, Rampazzo E, Bortolozzi R, Rruga F, Zeni I, Manfreda L, Marchioro C, Canton M, Cani A, Magni R, Luchini A, Bresolin S, Viola G, Persano L. Mariotto E, et al. Among authors: manfreda l. Acta Neuropathol Commun. 2023 Nov 17;11(1):183. doi: 10.1186/s40478-023-01679-7. Acta Neuropathol Commun. 2023. PMID: 37978570 Free PMC article.
Design, synthesis, and biological investigation of selective human carbonic anhydrase II, IX, and XII inhibitors using 7-aryl/heteroaryl triazolopyrimidines bearing a sulfanilamide scaffold.
Romagnoli R, De Ventura T, Manfredini S, Baldini E, Supuran CT, Nocentini A, Brancale A, Bortolozzi R, Manfreda L, Viola G. Romagnoli R, et al. Among authors: manfreda l. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2270180. doi: 10.1080/14756366.2023.2270180. Epub 2023 Oct 18. J Enzyme Inhib Med Chem. 2023. PMID: 37850364 Free PMC article.
Collagen VI sustains cell stemness and chemotherapy resistance in glioblastoma.
Cescon M, Rampazzo E, Bresolin S, Da Ros F, Manfreda L, Cani A, Della Puppa A, Braghetta P, Bonaldo P, Persano L. Cescon M, et al. Among authors: manfreda l. Cell Mol Life Sci. 2023 Jul 28;80(8):233. doi: 10.1007/s00018-023-04887-5. Cell Mol Life Sci. 2023. PMID: 37505240 Free PMC article.
Identification of pyrrolo[3',4':3,4]cyclohepta[1,2-d][1,2]oxazoles as promising new candidates for the treatment of lymphomas.
Barreca M, Spanò V, Rocca R, Bivacqua R, Gualtieri G, Raimondi MV, Gaudio E, Bortolozzi R, Manfreda L, Bai R, Montalbano A, Alcaro S, Hamel E, Bertoni F, Viola G, Barraja P. Barreca M, et al. Among authors: manfreda l. Eur J Med Chem. 2023 Jun 5;254:115372. doi: 10.1016/j.ejmech.2023.115372. Epub 2023 Apr 12. Eur J Med Chem. 2023. PMID: 37068384 Free PMC article.
Design, Synthesis and Biological Investigation of 2-Anilino Triazolopyrimidines as Tubulin Polymerization Inhibitors with Anticancer Activities.
Romagnoli R, Oliva P, Prencipe F, Manfredini S, Budassi F, Brancale A, Ferla S, Hamel E, Corallo D, Aveic S, Manfreda L, Mariotto E, Bortolozzi R, Viola G. Romagnoli R, et al. Among authors: manfreda l. Pharmaceuticals (Basel). 2022 Aug 21;15(8):1031. doi: 10.3390/ph15081031. Pharmaceuticals (Basel). 2022. PMID: 36015179 Free PMC article.