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Page 1
PAX5::AUTS2 childhood B-ALL: a relapse-prone genetic subtype with frequent central nervous system involvement and a poor outcome.
Caye-Eude A, Fazio G, Pastorczak A, Boer JM, Steinemann D, Ganguli D, Sonneveld E, Haslinger S, D'Andrea L, Bradtke J, Lopes BA, Zaliova M, Escherich G, König M, Fortschegger K, Inthal A, Stasevich I, Emerenciano M, Trka J, Castillo L, Parihar M, Moorman AV, Bergmann AK, den Boer ML, Młynarski W, Cazzaniga G, Cavé H, Nebral K, Schinnerl D, Strehl S. Caye-Eude A, et al. Among authors: trka j. Leukemia. 2024 Dec 19. doi: 10.1038/s41375-024-02502-5. Online ahead of print. Leukemia. 2024. PMID: 39702796 No abstract available.
Rewired glutamate metabolism diminishes cytostatic action of L-asparaginase.
Hlozkova K, Vasylkivska M, Boufersaoui A, Marzullo B, Kolarik M, Alquezar-Artieda N, Shaikh M, Alaei NF, Zaliova M, Zwyrtkova M, Bakardijeva-Mihaylova V, Alberich-Jorda M, Trka J, Tennant DA, Starkova J. Hlozkova K, et al. Among authors: trka j. Cancer Lett. 2024 Nov 28;605:217242. doi: 10.1016/j.canlet.2024.217242. Epub 2024 Sep 11. Cancer Lett. 2024. PMID: 39270769 Free article.
Distinct pattern of genomic breakpoints in CML and BCR::ABL1-positive ALL: analysis of 971 patients.
Hovorkova L, Winkowska L, Skorepova J, Krumbholz M, Benesova A, Polivkova V, Alten J, Bardini M, Meyer C, Kim R, Trahair TN, Clappier E, Chiaretti S, Henderson M, Sutton R, Sramkova L, Stary J, Polakova KM, Marschalek R, Metzler M, Cazzaniga G, Cario G, Trka J, Zaliova M, Zuna J. Hovorkova L, et al. Among authors: trka j. Mol Cancer. 2024 Jul 5;23(1):138. doi: 10.1186/s12943-024-02053-4. Mol Cancer. 2024. PMID: 38970095 Free PMC article.
Biologic and Clinical Analysis of Childhood Gamma Delta T-ALL Identifies LMO2/STAG2 Rearrangements as Extremely High Risk.
Kimura S, Park CS, Montefiori LE, Iacobucci I, Pölönen P, Gao Q, Arnold ED, Attarbaschi A, Brown A, Buldini B, Caldwell KJ, Chang Y, Chen C, Cheng C, Cheng Z, Choi J, Conter V, Crews KR, de Groot-Kruseman HA, Deguchi T, Eguchi M, Muhle HE, Elitzur S, Escherich G, Freeman BB 3rd, Gu Z, Han K, Horibe K, Imamura T, Jeha S, Kato M, Chiew KH, Khan T, Kicinski M, Köhrer S, Kornblau SM, Kotecha RS, Li CK, Liu YC, Locatelli F, Luger SM, Paietta EM, Manabe A, Marquart HV, Masetti R, Maybury M, Mazilier P, Meijerink JPP, Mitchell S, Miyamura T, Moore AS, Oshima K, Pawinska-Wasikowska K, Pieters R, Prater MS, Pruett-Miller SM, Pui CH, Qu C, Reiterova M, Reyes N, Roberts KG, Rowe JM, Sato A, Schmiegelow K, Schrappe M, Shen S, Skoczeń S, Spinelli O, Stary J, Svaton M, Takagi M, Takita J, Tang Y, Teachey DT, Thomas PG, Tomizawa D, Trka J, Varotto E, Vincent TL, Yang JJ, Yeoh AEJ, Zhou Y, Zimmermann M, Inaba H, Mullighan CG. Kimura S, et al. Among authors: trka j. Cancer Discov. 2024 Oct 4;14(10):1838-1859. doi: 10.1158/2159-8290.CD-23-1452. Cancer Discov. 2024. PMID: 38916500
The gray area of RQ-PCR-based measurable residual disease: subdividing the "positive, below quantitative range" category.
Kotrova M, Fronkova E, Svaton M, Drandi D, Schön F, Hoogeveen P, Hancock J, Skotnicova A, Schilhabel A, Eckert C, Clappier E, Cazzaniga G, Schäfer BW, van Dongen JJM, Ritgen M, Pott C, van der Velden VHJ, Trka J, Brüggemann M. Kotrova M, et al. Among authors: trka j. Leukemia. 2024 Jul;38(7):1617-1620. doi: 10.1038/s41375-024-02265-z. Epub 2024 May 17. Leukemia. 2024. PMID: 38760480 Free PMC article. No abstract available.
Analysis of measurable residual disease by IG/TR gene rearrangements: quality assurance and updated EuroMRD guidelines.
van der Velden VHJ, Dombrink I, Alten J, Cazzaniga G, Clappier E, Drandi D, Eckert C, Fronkova E, Hancock J, Kotrova M, Kraemer R, Montonen M, Pfeifer H, Pott C, Raff T, Trautmann H, Cavé H, Schäfer BW, van Dongen JJM, Trka J, Brüggemann M; EuroMRD Consortium. van der Velden VHJ, et al. Among authors: trka j. Leukemia. 2024 Jun;38(6):1315-1322. doi: 10.1038/s41375-024-02272-0. Epub 2024 May 14. Leukemia. 2024. PMID: 38744919 Free PMC article.
Biologic and clinical features of childhood gamma delta T-ALL: identification of STAG2/LMO2 γδ T-ALL as an extremely high risk leukemia in the very young.
Kimura S, Polonen P, Montefiori L, Park CS, Iacobucci I, Yeoh AE, Attarbaschi A, Moore AS, Brown A, Manabe A, Buldini B, Freeman BB, Chen C, Cheng C, Kean Hui C, Li CK, Pui CH, Qu C, Tomizawa D, Teachey DT, Varotto E, Paietta EM, Arnold ED, Locatelli F, Escherich G, Elisa Muhle H, Marquart HV, de Groot-Kruseman HA, Rowe JM, Stary J, Trka J, Choi JK, Meijerink JPP, Yang JJ, Takita J, Pawinska-Wasikowska K, Roberts KG, Han K, Caldwell KJ, Schmiegelow K, Crews KR, Eguchi M, Schrappe M, Zimmerman M, Takagi M, Maybury M, Svaton M, Reiterova M, Kicinski M, Prater MS, Kato M, Reyes N, Spinelli O, Thomas P, Mazilier P, Gao Q, Masetti R, Kotecha RS, Pieters R, Elitzur S, Luger SM, Mitchell S, Pruett-Miller SM, Shen S, Jeha S, Köhrer S, Kornblau SM, Skoczeń S, Miyamura T, Vincent TL, Imamura T, Conter V, Tang Y, Liu YC, Chang Y, Gu Z, Cheng Z, Yinmei Z, Inaba H, Mullighan CG. Kimura S, et al. Among authors: trka j. medRxiv [Preprint]. 2023 Nov 8:2023.11.06.23298028. doi: 10.1101/2023.11.06.23298028. medRxiv. 2023. PMID: 37986997 Free PMC article. Preprint.
Loss of function of ENT3 drives histiocytosis and inflammation through TLR-MAPK signaling.
Shiloh R, Lubin R, David O, Geron I, Okon E, Hazan I, Zaliova M, Amarilyo G, Birger Y, Borovitz Y, Brik D, Broides A, Cohen-Kedar S, Harel L, Kristal E, Kozlova D, Ling G, Shapira Rootman M, Shefer Averbuch N, Spielman S, Trka J, Izraeli S, Yona S, Elitzur S. Shiloh R, et al. Among authors: trka j. Blood. 2023 Nov 16;142(20):1740-1751. doi: 10.1182/blood.2023020714. Blood. 2023. PMID: 37738562 Free article.
183 results