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Plant MDL proteins synergize with the cytokine MIF at CXCR2 and CXCR4 receptors in human cells.
Spiller L, Manjula R, Leissing F, Basquin J, Bourilhon P, Sinitski D, Brandhofer M, Levecque S, Gerra S, Sabelleck B, Zhang L, Feederle R, Flatley A, Hoffmann A, Panstruga R, Bernhagen J, Lolis E. Spiller L, et al. Among authors: hoffmann a. Sci Signal. 2023 Nov 21;16(812):eadg2621. doi: 10.1126/scisignal.adg2621. Epub 2023 Nov 21. Sci Signal. 2023. PMID: 37988455
Studying the Pro-Migratory Effects of MIF.
Hoffmann A, Zwißler LC, El Bounkari O, Bernhagen J. Hoffmann A, et al. Methods Mol Biol. 2020;2080:1-18. doi: 10.1007/978-1-4939-9936-1_1. Methods Mol Biol. 2020. PMID: 31745866
Designed CXCR4 mimic acts as a soluble chemokine receptor that blocks atherogenic inflammation by agonist-specific targeting.
Kontos C, El Bounkari O, Krammer C, Sinitski D, Hille K, Zan C, Yan G, Wang S, Gao Y, Brandhofer M, Megens RTA, Hoffmann A, Pauli J, Asare Y, Gerra S, Bourilhon P, Leng L, Eckstein HH, Kempf WE, Pelisek J, Gokce O, Maegdefessel L, Bucala R, Dichgans M, Weber C, Kapurniotu A, Bernhagen J. Kontos C, et al. Among authors: hoffmann a. Nat Commun. 2020 Nov 25;11(1):5981. doi: 10.1038/s41467-020-19764-z. Nat Commun. 2020. PMID: 33239628 Free PMC article.
Heterocomplexes between the atypical chemokine MIF and the CXC-motif chemokine CXCL4L1 regulate inflammation and thrombus formation.
Brandhofer M, Hoffmann A, Blanchet X, Siminkovitch E, Rohlfing AK, El Bounkari O, Nestele JA, Bild A, Kontos C, Hille K, Rohde V, Fröhlich A, Golemi J, Gokce O, Krammer C, Scheiermann P, Tsilimparis N, Sachs N, Kempf WE, Maegdefessel L, Otabil MK, Megens RTA, Ippel H, Koenen RR, Luo J, Engelmann B, Mayo KH, Gawaz M, Kapurniotu A, Weber C, von Hundelshausen P, Bernhagen J. Brandhofer M, et al. Among authors: hoffmann a. Cell Mol Life Sci. 2022 Sep 12;79(10):512. doi: 10.1007/s00018-022-04539-0. Cell Mol Life Sci. 2022. PMID: 36094626 Free PMC article.
Engineering an inducible leukemia-associated fusion protein enables large-scale ex vivo production of functional human phagocytes.
Windisch R, Soliman S, Hoffmann A, Chen-Wichmann L, Danese A, Vosberg S, Bravo J, Lutz S, Kellner C, Fischer A, Gebhard C, Redondo Monte E, Hartmann L, Schneider S, Beier F, Strobl CD, Weigert O, Peipp M, Schündeln M, Stricker SH, Rehli M, Bernhagen J, Humpe A, Klump H, Brendel C, Krause DS, Greif PA, Wichmann C. Windisch R, et al. Among authors: hoffmann a. Proc Natl Acad Sci U S A. 2024 Jun 18;121(25):e2312499121. doi: 10.1073/pnas.2312499121. Epub 2024 Jun 10. Proc Natl Acad Sci U S A. 2024. PMID: 38857395 Free PMC article.
CD74 is a functional MIF receptor on activated CD4+ T cells.
Zhang L, Woltering I, Holzner M, Brandhofer M, Schaefer CC, Bushati G, Ebert S, Yang B, Muenchhoff M, Hellmuth JC, Scherer C, Wichmann C, Effinger D, Hübner M, El Bounkari O, Scheiermann P, Bernhagen J, Hoffmann A. Zhang L, et al. Among authors: hoffmann a. Cell Mol Life Sci. 2024 Jul 11;81(1):296. doi: 10.1007/s00018-024-05338-5. Cell Mol Life Sci. 2024. PMID: 38992165 Free PMC article.
The regional distribution of catheter ablations of atrial fibrillation and atrial flutter in Poland in 2023.
Wita K, Dyrbuś M, Kowalski O, Wita M, Myrda K, Hoffmann A, Błachut A, Jadczyk T, Mizia-Stec K, Gołba K, Stępińska J, Witkowski A, Gąsior M, Kalarus Z, Banasiak W. Wita K, et al. Among authors: hoffmann a. Kardiol Pol. 2025 Jan 2. doi: 10.33963/v.phj.103818. Online ahead of print. Kardiol Pol. 2025. PMID: 39743903 Free article. No abstract available.
2,773 results