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Unrestrained cleavage of Roquin-1 by MALT1 induces spontaneous T cell activation and the development of autoimmunity.
Schmidt H, Raj T, O'Neill TJ, Muschaweckh A, Giesert F, Negraschus A, Hoefig KP, Behrens G, Esser L, Baumann C, Feederle R, Plaza-Sirvent C, Geerlof A, Gewies A, Isay SE, Ruland J, Schmitz I, Wurst W, Korn T, Krappmann D, Heissmeyer V. Schmidt H, et al. Among authors: ruland j. Proc Natl Acad Sci U S A. 2023 Nov 28;120(48):e2309205120. doi: 10.1073/pnas.2309205120. Epub 2023 Nov 21. Proc Natl Acad Sci U S A. 2023. PMID: 37988467 Free PMC article.
Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation.
Oeckinghaus A, Wegener E, Welteke V, Ferch U, Arslan SC, Ruland J, Scheidereit C, Krappmann D. Oeckinghaus A, et al. Among authors: ruland j. EMBO J. 2007 Nov 14;26(22):4634-45. doi: 10.1038/sj.emboj.7601897. Epub 2007 Oct 18. EMBO J. 2007. PMID: 17948050 Free PMC article.
224 results