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Page 1
Development of Resistance to Type II JAK2 Inhibitors in MPN Depends on AXL Kinase and Is Targetable.
Codilupi T, Szybinski J, Arunasalam S, Jungius S, Dunbar AC, Stivala S, Brkic S, Albrecht C, Vokalova L, Yang JL, Buczak K, Ghosh N, Passweg JR, Rovo A, Angelillo-Scherrer A, Pankov D, Dirnhofer S, Levine RL, Koche R, Meyer SC. Codilupi T, et al. Among authors: stivala s. Clin Cancer Res. 2024 Feb 1;30(3):586-599. doi: 10.1158/1078-0432.CCR-23-0163. Clin Cancer Res. 2024. PMID: 37992313 Free PMC article.
Targeting compensatory MEK/ERK activation increases JAK inhibitor efficacy in myeloproliferative neoplasms.
Stivala S, Codilupi T, Brkic S, Baerenwaldt A, Ghosh N, Hao-Shen H, Dirnhofer S, Dettmer MS, Simillion C, Kaufmann BA, Chiu S, Keller M, Kleppe M, Hilpert M, Buser AS, Passweg JR, Radimerski T, Skoda RC, Levine RL, Meyer SC. Stivala S, et al. J Clin Invest. 2019 Mar 4;129(4):1596-1611. doi: 10.1172/JCI98785. eCollection 2019 Mar 4. J Clin Invest. 2019. PMID: 30730307 Free PMC article.
Dual targeting of JAK2 and ERK interferes with the myeloproliferative neoplasm clone and enhances therapeutic efficacy.
Brkic S, Stivala S, Santopolo A, Szybinski J, Jungius S, Passweg JR, Tsakiris D, Dirnhofer S, Hutter G, Leonards K, Lischer HEL, Dettmer MS, Neel BG, Levine RL, Meyer SC. Brkic S, et al. Among authors: stivala s. Leukemia. 2021 Oct;35(10):2875-2884. doi: 10.1038/s41375-021-01391-2. Epub 2021 Sep 3. Leukemia. 2021. PMID: 34480104 Free PMC article.
Inhibition of Vascular c-Jun N-Terminal Kinase 2 Improves Obesity-Induced Endothelial Dysfunction After Roux-en-Y Gastric Bypass.
Doytcheva P, Bächler T, Tarasco E, Marzolla V, Engeli M, Pellegrini G, Stivala S, Rohrer L, Tona F, Camici GG, Vanhoutte PM, Matter CM, Lutz TA, Lüscher TF, Osto E. Doytcheva P, et al. Among authors: stivala s. J Am Heart Assoc. 2017 Nov 14;6(11):e006441. doi: 10.1161/JAHA.117.006441. J Am Heart Assoc. 2017. PMID: 29138180 Free PMC article.
Dronedarone reduces arterial thrombus formation.
Breitenstein A, Sluka SH, Akhmedov A, Stivala S, Steffel J, Camici GG, Riem HH, Beer HJ, Studt JD, Duru F, Luscher TF, Tanner FC. Breitenstein A, et al. Among authors: stivala s. Basic Res Cardiol. 2012 Nov;107(6):302. doi: 10.1007/s00395-012-0302-4. Epub 2012 Sep 29. Basic Res Cardiol. 2012. PMID: 23052639 Free article.
Sirt6 deletion in bone marrow-derived cells increases atherosclerosis - Central role of macrophage scavenger receptor 1.
Arsiwala T, Pahla J, van Tits LJ, Bisceglie L, Gaul DS, Costantino S, Miranda MX, Nussbaum K, Stivala S, Blyszczuk P, Weber J, Tailleux A, Stein S, Paneni F, Beer JH, Greter M, Becher B, Mostoslavsky R, Eriksson U, Staels B, Auwerx J, Hottiger MO, Lüscher TF, Matter CM. Arsiwala T, et al. Among authors: stivala s. J Mol Cell Cardiol. 2020 Feb;139:24-32. doi: 10.1016/j.yjmcc.2020.01.002. Epub 2020 Jan 21. J Mol Cell Cardiol. 2020. PMID: 31972266
Elevated HbA1c is not associated with recurrent venous thromboembolism in the elderly, but with all-cause mortality- the SWEETCO 65+ study.
Mathis A, Villiger L, Reiner MF, Egloff M, Schmid HR, Stivala S, Limacher A, Mean M, Aujesky D, Rodondi N, Angelillo-Scherrer A, Righini M, Staub D, Aschwanden M, Frauchiger B, Osterwalder J, Kucher N, Matter CM, Banyai M, Hugli O, Beer JH. Mathis A, et al. Among authors: stivala s. Sci Rep. 2020 Feb 12;10(1):2495. doi: 10.1038/s41598-020-59173-2. Sci Rep. 2020. PMID: 32051462 Free PMC article.
58 results