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The neutral CB1 antagonist AM6527 reduces ethanol seeking, binge-like consumption, reinforcing, and withdrawal effects in male and female mice.
Raghav JG, Kumar H, Ji L, Vemuri K, Makriyannis A, Suh J, Leonard MZ, Dang V, Ty C, Marandola S, Kane N, Witt AS, Shaqour S, Miczek KA. Raghav JG, et al. Among authors: vemuri k. Psychopharmacology (Berl). 2024 Mar;241(3):427-443. doi: 10.1007/s00213-023-06500-w. Epub 2023 Nov 25. Psychopharmacology (Berl). 2024. PMID: 38001264
Translational strategies for therapeutic development in nicotine addiction: rethinking the conventional bench to bedside approach.
Le Foll B, Pushparaj A, Pryslawsky Y, Forget B, Vemuri K, Makriyannis A, Trigo JM. Le Foll B, et al. Among authors: vemuri k. Prog Neuropsychopharmacol Biol Psychiatry. 2014 Jul 3;52:86-93. doi: 10.1016/j.pnpbp.2013.10.009. Epub 2013 Oct 17. Prog Neuropsychopharmacol Biol Psychiatry. 2014. PMID: 24140878 Free PMC article. Review.
Cannabinoid withdrawal in mice: inverse agonist vs neutral antagonist.
Tai S, Nikas SP, Shukla VG, Vemuri K, Makriyannis A, Järbe TU. Tai S, et al. Among authors: vemuri k. Psychopharmacology (Berl). 2015 Aug;232(15):2751-61. doi: 10.1007/s00213-015-3907-0. Epub 2015 Mar 15. Psychopharmacology (Berl). 2015. PMID: 25772338 Free PMC article.
Blockade of Nicotine and Cannabinoid Reinforcement and Relapse by a Cannabinoid CB1-Receptor Neutral Antagonist AM4113 and Inverse Agonist Rimonabant in Squirrel Monkeys.
Schindler CW, Redhi GH, Vemuri K, Makriyannis A, Le Foll B, Bergman J, Goldberg SR, Justinova Z. Schindler CW, et al. Among authors: vemuri k. Neuropsychopharmacology. 2016 Aug;41(9):2283-93. doi: 10.1038/npp.2016.27. Epub 2016 Feb 18. Neuropsychopharmacology. 2016. PMID: 26888056 Free PMC article.
The CB1 Neutral Antagonist AM4113 Retains the Therapeutic Efficacy of the Inverse Agonist Rimonabant for Nicotine Dependence and Weight Loss with Better Psychiatric Tolerability.
Gueye AB, Pryslawsky Y, Trigo JM, Poulia N, Delis F, Antoniou K, Loureiro M, Laviolette SR, Vemuri K, Makriyannis A, Le Foll B. Gueye AB, et al. Among authors: vemuri k. Int J Neuropsychopharmacol. 2016 Dec 30;19(12):pyw068. doi: 10.1093/ijnp/pyw068. Print 2016 Dec. Int J Neuropsychopharmacol. 2016. PMID: 27493155 Free PMC article.
Crystal Structure of the Human Cannabinoid Receptor CB1.
Hua T, Vemuri K, Pu M, Qu L, Han GW, Wu Y, Zhao S, Shui W, Li S, Korde A, Laprairie RB, Stahl EL, Ho JH, Zvonok N, Zhou H, Kufareva I, Wu B, Zhao Q, Hanson MA, Bohn LM, Makriyannis A, Stevens RC, Liu ZJ. Hua T, et al. Among authors: vemuri k. Cell. 2016 Oct 20;167(3):750-762.e14. doi: 10.1016/j.cell.2016.10.004. Cell. 2016. PMID: 27768894 Free PMC article.
84 results