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In vivo reprogramming leads to premature death linked to hepatic and intestinal failure.
Parras A, Vílchez-Acosta A, Desdín-Micó G, Picó S, Mrabti C, Montenegro-Borbolla E, Maroun CY, Haghani A, Brooke R, Del Carmen Maza M, Rechsteiner C, Battiston F, Branchina C, Perez K, Horvath S, Bertelli C, Sempoux C, Ocampo A. Parras A, et al. Among authors: rechsteiner c. Nat Aging. 2023 Dec;3(12):1509-1520. doi: 10.1038/s43587-023-00528-5. Epub 2023 Nov 27. Nat Aging. 2023. PMID: 38012287
ATAC-clock: An aging clock based on chromatin accessibility.
Morandini F, Rechsteiner C, Perez K, Praz V, Lopez Garcia G, Hinte LC, von Meyenn F, Ocampo A. Morandini F, et al. Among authors: rechsteiner c. Geroscience. 2024 Apr;46(2):1789-1806. doi: 10.1007/s11357-023-00986-0. Epub 2023 Nov 4. Geroscience. 2024. PMID: 37924441 Free PMC article.
DNA repair-deficient premature aging models display accelerated epigenetic age.
Perez K, Parras A, Picó S, Rechsteiner C, Haghani A, Brooke R, Mrabti C, Schoenfeldt L, Horvath S, Ocampo A. Perez K, et al. Among authors: rechsteiner c. Aging Cell. 2024 Feb;23(2):e14058. doi: 10.1111/acel.14058. Epub 2023 Dec 22. Aging Cell. 2024. PMID: 38140713 Free PMC article.