Laraia L - Search Results

1

Identification of non-conventional small molecule degraders and stabilizers of squalene synthase.

Hoock JGF, Rossetti C, Bilgin M, Depta L, Enemark-Rasmussen K, Christianson JC, Laraia L. Hoock JGF, et al. Among authors: laraia l. Chem Sci. 2023 Oct 18;14(45):12973-12983. doi: 10.1039/d3sc04064j. eCollection 2023 Nov 22. Chem Sci. 2023. PMID: 38023519 Free PMC article.

2

Unravelling the Mode of Action of Furanoheliangolides through Total Synthesis and Chemical Proteomics.

Hoock JGF, Laraia L. Hoock JGF, et al. Among authors: laraia l. ACS Cent Sci. 2021 Jun 23;7(6):923-925. doi: 10.1021/acscentsci.1c00542. Epub 2021 May 27. ACS Cent Sci. 2021. PMID: 34235252 Free PMC article. No abstract available.

3

Structure, function and small molecule modulation of intracellular sterol transport proteins.

Depta L, Whitmarsh-Everiss T, Laraia L. Depta L, et al. Among authors: laraia l. Bioorg Med Chem. 2022 Aug 15;68:116856. doi: 10.1016/j.bmc.2022.116856. Epub 2022 Jun 6. Bioorg Med Chem. 2022. PMID: 35716590 Free article. Review.

4

Thermal Proteome Profiling Reveals Distinct Target Selectivity for Differentially Oxidized Oxysterols.

Rossetti C, Laraia L. Rossetti C, et al. Among authors: laraia l. ACS Chem Biol. 2022 Jul 15;17(7):1677-1684. doi: 10.1021/acschembio.2c00383. Epub 2022 Jun 28. ACS Chem Biol. 2022. PMID: 35763711

5

Identification of Biologically Diverse Tetrahydronaphthalen-2-ols through the Synthesis and Phenotypic Profiling of Chemically Diverse, Estradiol-Inspired Compounds.

Whitmarsh-Everiss T, Wang Z, Hauberg Hansen C, Depta L, Sassetti E, Rafn Dan O, Pahl A, Sievers S, Laraia L. Whitmarsh-Everiss T, et al. Among authors: laraia l. Chembiochem. 2023 Mar 1;24(5):e202200555. doi: 10.1002/cbic.202200555. Epub 2023 Feb 7. Chembiochem. 2023. PMID: 36594441

6

Small molecule probes for targeting autophagy.

Whitmarsh-Everiss T, Laraia L. Whitmarsh-Everiss T, et al. Among authors: laraia l. Nat Chem Biol. 2021 Jun;17(6):653-664. doi: 10.1038/s41589-021-00768-9. Epub 2021 May 25. Nat Chem Biol. 2021. PMID: 34035513 Review.

7

Making bubbles: Targeting VPS41 induces vacuolization and methuosis.

Dekker NJ, Laraia L. Dekker NJ, et al. Among authors: laraia l. Cell Chem Biol. 2023 Feb 16;30(2):127-129. doi: 10.1016/j.chembiol.2023.01.008. Cell Chem Biol. 2023. PMID: 36800990 Free article.

8

Small-Molecule Inhibitors of Reactive Oxygen Species Production.

Sassetti E, Clausen MH, Laraia L. Sassetti E, et al. Among authors: laraia l. J Med Chem. 2021 May 13;64(9):5252-5275. doi: 10.1021/acs.jmedchem.0c01914. Epub 2021 Apr 15. J Med Chem. 2021. PMID: 33856791 Review.

9

Redshifted and thermally bistable one-way quantitative hemithioindigo-derived photoswitches enabled by isomer-specific excited state intramolecular proton transfer.

Krell-Jørgensen M, Zulfikri H, Bonnevie MG, Bro FS, Dohn AO, Laraia L. Krell-Jørgensen M, et al. Among authors: laraia l. Chem Commun (Camb). 2023 Jan 12;59(5):563-566. doi: 10.1039/d2cc05548a. Chem Commun (Camb). 2023. PMID: 36537010

10

Thermal proteome profiling identifies the membrane-bound purinergic receptor P2X4 as a target of the autophagy inhibitor indophagolin.

Carnero Corrales MA, Zinken S, Konstantinidis G, Rafehi M, Abdelrahman A, Wu YW, Janning P, Müller CE, Laraia L, Waldmann H. Carnero Corrales MA, et al. Among authors: laraia l. Cell Chem Biol. 2021 Dec 16;28(12):1750-1757.e5. doi: 10.1016/j.chembiol.2021.02.017. Epub 2021 Mar 15. Cell Chem Biol. 2021. PMID: 33725479 Free article.

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